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Anales de Otorrinolaringología Mexicana

Anales de Otorrinolaringología Mexicana
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2015, Number 4

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Otorrinolaringología 2015; 60 (4)

Relation between hearing loss and administration of insulin in patients with diabetes type 2

Sánchez-Balderas VR, Fernández-Olvera MG
Full text How to cite this article

Language: Spanish
References: 11
Page: 252-256
PDF size: 254.30 Kb.


Key words:

hearing loss, diabetes mellitus 2, insulin.

ABSTRACT

Background: Diabetes mellitus is a chronic-degenerative disease related to sensorineural hearing los since 19th century. Hearing loss has been related to time of evolution of diabetes mellitus and, in some studies, with microalbuminuria.
Objective: To assess the relation between sensorineural hearing loss and administration of insulin in patients with diabetes mellitus 2.
Material and method: A prolective study was made with 47 patients of both sexes, from 16 to 65 years old, from the consultation of Endocrinology, Ophthalmology and Internal Medicine Services of Central Hospital Dr. Dr. Ignacio Morones Prieto, San Luis Potosí, Mexico, without symptoms of disease of media ear, sudden hearing loss, prescription of ototoxic drugs, exposure to intense noises or with some cortipathy previously diagnosed. Patients were submitted to tonal audiometry and time of diagnosis of diabetes mellitus, administration of insulin as part of treatment and age. Bivariate statistics and linear regression tests were done.
Results: 47 patients were assessed; 24 were male. Mean age was of 55 years (32-65). Mean of all frequencies of both ears was of 35.02 dB, finding greater damage in 4 and 8 kHz, with mean of 40.42 and 43.29 dB, respectively. Time of diagnosis of diabetes was of 13.79 years (2-25 years). When doing a t paired, p‹0.05 was obtained for administration of insulin. By linear regression a p‹0.05 was obtained for prescription of insulin and for time of evolution of diabetes mellitus.
Conclusions: Administration of insulin is related to sensorineural hearing loss in patients with diabetes mellitus type 2.


REFERENCES

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  2. Okhovat SA, Moaddab MH, Okhovat SH, Al-Azab AA, et al. Evaluation of hearing loss in juvenile insulin dependent patients with diabetes mellitus. J Res Med Sci 2011;16:179-183.

  3. Di Leo MA, Di Nardo W, Cercone S, Ciervo A, et al. Cochlear dysfunction in IDDM patients with subclinical peripheral neuropathy. Diabetes Care 1997;20:824-828.

  4. Ottaviani F, Dozio N, Neglia CB, Riccio S, Scarvini M. Absence of otoacustic emissions in insulin-dependent diabetic patients: is there evidence for diabetic cochleopathy. J Diabetes Complications 2002;16:338-343.

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  9. Katz MH. Multivariable analysis: a primer for readers of medical research. Ann Intern Med 2003;138:644-650.

  10. Babyak MA. What you see may not be what you get: a brief, nontechnical introduction to overfitting in regression-type models. Psychosom Med 2004;66:411-421.

  11. Wackym PA, Linthicum FH Jr. Diabetes mellitus and hearing loss: clinical and histopathologic relationship. Am J Otol 1986;7:176-182.




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Otorrinolaringología. 2015;60