2015, Number 3
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ABSTRACTSarcopenic Obesity is a clinical and pathophysiological entity that implies disability and risk of mortality. Its definition has been subject of consensus by The European Working Group on Sarcopenia in Older People (EWGSOP) and the International Working Group on Sarcopenia (IWGS). Thanks to the studies conducted by Baumgartner and Janssen, the standardization of sarcopenia´s diagnosis has been determinated by the measurement of the appendicular muscle mass index using the height (ASM/ht 2) and body weight (ASM/Wt) analyzed on the Dual-energy X-ray Absorptiometry (DXA) and the Bioelectrical Impedance Analysis (BIA). Obesity is assessed by the body mass index and the body fat percentage. Recent meta-analysis has estimated an incidence of Sarcopenic Obesity from 2 to 20%. Sarcopenic Obesity has been characterized by insulin, resistance and inflammation. The adipocyte has been implicated in maintaining this process. There have been studies that suggest an approach and intervention based on the body composition and the metabolic risk.
Fielding RA, Vellas B, Evans WJ, y col. Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequence;J Am Med Dir Assoc.; 2011; 12(4): 249–256. (Manuscrito del autor consultado en PubMed Central®)
KimY; Chung Y; Lee D; y col. Prevalence of Sarcopenia and Sarcopenic Obesity in the Korean Population Based on the Fourth Korean National Health and Nutritional Examination Surveys. J Gerontol A BiolSci Med Sci.; 2012;67(10):1107–1113
Baumgartner R; Koehler K; Gallagher D; y col. Epidemiology of Sarcopenia among the Elderly in New Mexico Am.J. Epidemiol; 1998;147:755-63.
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, y col. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing; 2010;39(4):412-23.
Abellan Van Kan G., Cedarbaum J.M.,Cesari M; y col. Sarcopenia: Biomarkers And Imaging (International Conference On Sarcopenia Research) The Journal of Nutrition, Health & Aging. 2011; 10: 834:846
Donin L.M; Poggiogalle E; Migliaccio S; y col. Body composition in sarcopenic obesity: systematic review of the literature Mediterr. J. Nutr.Metab. 2013;6:191–198.
Mathus-Vliegen E.M. Obesity and the Elderly J.Clin. Gastroenterol; 2012;46:533–544.
Schaap L; Koster A; Visser M (2013) Adiposity, Muscle Mass, and Muscle Strength in Relation to Functional Decline in Older Persons Epidemiologic Reviews 2013
Zoico E, Francesco V, Guralnik JM, y col (2004) Physical disability and muscular strength in relation to obesity and different body composition indexes in a sample of healthy elderly women International Journal of Obesity 28, 234–241
Domiciano D;.Figueiredo C, Lopes J; OsteoporosInt (2013) 24:595–603 DOI 10.1007/s00198-012-2002-1 Discriminating sarcopenia in community-dwelling older women with high frequency of overweight/obesity: the São Paulo Ageing & Health Study (SPAH)
Lipschitz DA. (1994) Screening for nutritional status in the elderly. Prim Care. ;21:55–67
Kelly TL, Wilson KE, Heymsfield SB (2009) Dual Energy X-Ray Absorptiometry Body Composition Reference Values from NHANES. PLoS ONE 4(9): e7038. doi:10.1371/journal.pone.0007038
Baumgartner RN, Wayne SJ, Waters DL, y col. (2004) Sarcopenic obesity predicts instrumental activities of daily living disability in the elderly. Obes Res.;12:1995–2004.
EPIDOS Rolland Y, Lauwers-Cances V, Cristini C, y col (2009) Difficulties with physical function associated with obesity, sarcopenia, and sarcopenic-obesity in community-dwelling elderly women: the EPIDOS (EPIDemiologie de l’OSteoporose) Study. Am J Clin Nutr;89:1895–900
Gómez-Cabello A; G. Rodríguez V; Vila- Maldonado S; y col;(2012) Revisión, Envejecimiento y composición corporal: la obesidad sarcopénica en España Nutr Hosp.;27(1):22-30
Kohara K, (2013)Sarcopenic obesity in aging population: current status and future directions for research Endocrine. DOI 10.1007/s12020- 013-9992-0
Janssen I, Heymsfield SB, Ross R (2002). Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc;50:889 – 896
Prado C, Wells J, Smith SR;et al (2012) Review Sarcopenic obesity: A Critical appraisal of the current evidence Clinical Nutrition 31 583e601
Narici M; Maffulli N; (2010) Sarcopenia: characteristics, mechanisms and functional significance. British Medical Bulletin 2010;95: 139–15
StenholmS ., Harris T, Rantanen., Sarcopenic obesity - definition, etiology and consequences CurrOpinClinNutrMetab Care. 2008 November ; 11(6): 693–700
Goodpaster B, Park S, HarrisT , y col (2006)The Loss of Skeletal Muscle Strength, Mass, and Quality in Older Adults: The Health,Aging and Body Composition Study. Journal of Gerontology: MEDICAL SCIENCES 2006, Vol. 61A, No. 10, 1059–1064
Kohara K, Ochi M, Tabara Y, Nagai T, Igase M, y col. (2011) Leptin in Sarcopenic Visceral Obesity: Possible Link between Adipocytes and Myocytes. PLoS ONE 6(9): e24633. doi:10.1371/journal.pone.0024633
Migliaccio, S Francomano D; Bruzziches R; y col, (2013)Trunk Fat Negatively Influences Skeletal and Testicular Functions in Obese Men: Clinical Implications for the Aging Male International Journal of Endocrinologyconsultado en 15 de enero de 2013en http://dx.doi.org/10.1155/2013/18275
Reynolds S; Recent Developments in Obesity Research: Linkages between Obesity, Disability, and Physical Functioning CurrObes Rep.2013;2:267–274.
Abbatecola A.M; Chiodini P; Gallo C; y col Pulse wave velocity is associated with muscle mass decline: Health ABC study AGE. 2012;34:469–478
Strandberg T; Stenholm S; Strandberg A; y col (2013) The“ObesityParadox,”Frailty, Disability, and Mortality in Older Men: A Prospective, Longitudinal Cohort Study Am J Epidemiol. 2013;178(9):1452–1460
Lim S; KimJ; YoonJ; y col Sarcopenic Obesity: Prevalence and Association With Metabolic Syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA) Diabetes Care; 2010;33:1652–1654.
Waters D; Baumgartner R, Sarcopenia and Obesity ClinGeriatr Med 2011;27: 401–421