Coste MP, Jiménez BN, Leandro SV, Villalobos ZM

Language: Spanish
References: 9
Page: 20-24
PDF size: 678.81 Kb.

ABSTRACT

Purpura fulminans (PF) is an unusual manifestation of the skin associated with disseminated intravascular coagulation (DIC) secondary to infection or sepsis usually characterized by skin necrosis due to thrombosis of small vessels. It is a serious disease of acute onset with rapid progression and high mortality. A 34 years old male patient presented with a history of abdominal trauma splenectomy 10 years of age, without prophylactic antimicrobial therapy or prior pneumococcal vaccination, that sought medical attention for the development of generalized headache, malaise, pain in both lower limbs and ecchymotic skin rash in a period of 24 hours and then progressed to necrotic lesions in the skin and septic shock. Initial laboratories were consistent with DIC. Blood cultures and cerebrospinal fluid culture were positive for Streptococcus pneumonia.

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