medigraphic.com

2015, Number 3

Rev Cub de Reu 2015; 17 (3)

Neurobehçet

García-Rivero AA, Gonzalez-Argote J, Martínez LJP

Language: Spanish
References: 40
Page: 222-233
PDF size: 224.99 Kb.


ABSTRACT

Introduction: Behcet's disease is a multisystem inflammatory disorder of unknown etiology characterized by oral, genital ulcers and uveitis.
Objective: To describe the neurological manifestations in Behcet's disease.
Development: the neurological manifestations are divided intra-axial and extra-axial. The most common forms of presentation are the pyramidal disorders, signs of brainstem involvement and cognitive and/or behavioral disorders. Differential diagnoses are multiple sclerosis, cerebrovascular disease adult, meningitis and other neurological diseases. It is vital for accurate diagnosis means the use of neuroimaging, which demonstrate the correlation between symptoms and radiological findings. The concentration of IL-6 in cerebral spinal fluid is correlated with disease activity. Theoretically, any drug used for treatment of Behcet's disease, may be administered in the neurobehçet. But the pathophysiological differences and prognosis of this syndrome need a selection and adjustment of immunosuppressive therapy.
Conclusions: it was a challenge for modern medicine finding common features for the study of neurological manifestations of Behcet's disease.


REFERENCES

  1. Da-Lim Y, YouJae K, Bon San K, Yong-Gil K, Chang-Keun L, Bin Y. Neuro-behçet´s disease in South Korea: clinical characteristics and treatment response. International J of Rheumatic Diseases. 2014; 17:453-58.

  2. Landeyro J, Vidaur-Tello L, García-Fontgivell JF, Elguezábal A, Gené-Hijós M, Mayayo-Artal E. Neurobehçet: hallazgos clinicopatológicos de un caso de autopsia. Rev Neurol. 2008; 47 (11):575-78.

  3. Hirohata S. Histopathology of central nervous system lesions in Behçet’s disease. J NeurolSci. 2008;267:41-47.

  4. Kalra S, Silman A, Akman-Demir G, Bohlega S, Borhani-Haghighi A, Constantinescu SC, et. al. Diagnosis and management of Neuro-Behçet’s disease: international consensus recommendations. J Neurol. 2014;261:1662-176. doi: 10.1007/s00415-013-7209-3.

  5. Devatchi F, Assaad‐Khalil S, Calamia KT, Crook JE, Sadeghi‐Abdollahi B, Schirmer M, Rosa C M. The International Criteria for Behçet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. JEADV. [Internet]. 2014 [citado 2015 Ago 8];28:338-47. doi 10.1111/jdv.12107. Disponible en: http://www.researchgate.net/profile/Michael_Schirmer/publication/235738929_The_International_Criteria_for_Behet%27s_Disease_(ICBD)_a_collaborative_study_of_27_countries_on_the_sensitivity_and_specificity_of_the_new_criteria/links/0046351584e720aa32000000.pdf

  6. International Study Group for Behçet’s Disease. Criteria for diagnosis of Behçet’s disease. Lancet. 1990;335:1078-80.

  7. Almeida Dutra L, Roberto Gonçalves C, Braga-Neto P, Pedroso JL, Gabbai AA, Povoas Barsottini OG, et al. Atypical manifestations in Brazilian patients with neuro-Behçet’s disease. J Neurol. 2012; 259:1159-65. doi: 10.1007/s00415-011-6319-z.

  8. Noel N, Bernard R, Wechsler B, Resche-Rigon M, Depaz R, HuongBoutin DL et al. Long-Term Outcome of Neuro-Behçet'sDisease. Arthritis & Rheumatology. 2014; 66(5): 1306-14. DOI: 10.1002/art.38351.

  9. Yazici Y, Yazici H. Behçet’s Syndrome. New York: Ed. Springer Science + Business Media: LLC; 2010. doi: 10.1007/978-1-4419-5641-5_1.

  10. Álvarez Álvarez Gerardo, Martínez Delgado Francisco, González Cortiñas Modesto, Martín García C. Luis, Martínez Fraga Aurora. Enfermedad de Behcet: Informe de 5 casos. Rev cubana med [Internet]. 1998 Jun [citado 2015 Ago 6]; 37(2): 119-22. Disponible en: http://scieloprueba.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75231998000200009&lng=es

  11. Zayed H, Effat D, Nawito Z, Abdou AA, El Din MN, El-Refaei S, El-Einin KA. Silent central nervous system involvement in Egyptian Behçet's disease patients: clinical, psychiatric, and neuroimaging evaluation. Clin Rheumatol. 2011;30:1173–80.

  12. Fountain EM, Dhurandhar A. Neuro-Behçet’s Disease: An Unusual Cause of Headache. J Gen Intern Med. 2014;29(6):956-60. doi: 10.1007/s11606-014-2781-5.

  13. Pozo González Alberto, Barbán Fernández Leonor, Rodríguez del Valle Kenia M, Betancourt Fernández Isolina. Síndrome de Behçet: presentación de un caso. AMC [Internet]. 2010 Dic [citado 2015 Ago 11] ; 14(6): 1-7. Disponible en: http://scieloprueba.sld.cu/scielo.php?script=sci_arttext&pid=S1025-02552010000600016&lng=es

  14. Kose E, Kamisli S, DoganM, Tasolar S, Kahraman A, Oztanir MN et al. The Evaluation of Vertebrobasilar Artery System in Neuro-Behçet and Behçet Disease using Magnetic Resonance Angiography. The Anatomical Record 2014;297:1302-5.

  15. Mohammed RH, Nasef A, Kewan HH, Al Shaar M. Vascular neurobehçet disease: correlation with current disease activity forum and systemic vascular involvement. Clin Rheumatol. 2012;31:1033-40. doi: 10.1007/s10067-012-1953-0.

  16. Patel P, Steinschneider M, Boneparth A, Lantos G. Neuro-Behçet disease presenting with acute psychosis in an adolescent. J Child Neurol. [Internet]. 2014 [citado 2015 Ago 6];29(9):86-91. Disponible en: http://jcn.sagepub.com/content/early/2013/10/02/0883073813504137.full.pdf+html

  17. Rosaria Talarico R, Palagini L, d’Ascanio A, Elefante E, Ferrari C, Stagnaro C, et al. Epidemiology and Management of Neuropsychiatric Disorders in Behçet’s Syndrome. CNS Drugs. 2015; 29:189-96. doi: 10.1007/s40263-015-0228-0.

  18. Yesilot N, Bahar S, Yilmazer S, Mutlu M, Kurtuncu M, Tuncay R, Akman-Demir G. et al. Cerebral venous thrombosis in Behçet’s disease compared to those associated with other etiologies. J Neurol. [Internet]. 2009 [citado 2015 Ago 6];256(7):1134-42. Disponible en: http://link.springer.com/content/pdf/10.1007%2Fs00415-009-5088-4.pdf

  19. Saadoun D, Wechsler B, Resche-Rigon M, Trad S, Le Thi Huong D, Sbai A, Piette JC. Cerebral venous thrombosis in Behçet’s disease. Arthritis Care Res. [Internet]. 2009 [citado 2015 Ago 8];61:518-26. Disoible en: http://onlinelibrary.wiley.com/doi/10.1002/art.24393/pdf

  20. Aguiar de Sousa D, Mestre T, Ferro JM. Cerebral venous thrombosis in Behçet’s disease: a systematic review. J Neurol. 2011;258:719-27. DOI 10.1007/s00415-010-5885-9.

  21. Atasoy HT, Tunc TO, Unal AE, Emre U, Koca R, Esturk E, Inan LE. Peripheral nervous system involvement in patients with Behçet’s disease. Neurologist. 2007;13(4):225-30.

  22. Akbulut L, Gur G, Bodur H, Alli N, Borman P. Peripheral neuropathy in Behcet disease: an electroneurophysiological study. Clin Rheumatol. 2007;26:1240-44.

  23. M. Krämer M, Baumgärtel MW, Neuen-Jacob E, Berlit P. Myalgia in Neuro-Behçet’s disease. Medication side effects or expression of underlying disease? Rheumatol. 2008; 67:232-6. doi: 10.1007/s00393-008-0285-6.

  24. Yesilot N, Shehu M, Oktem-Tanor O, Serdaroglu P, Akman-Demir G. Silent neurological involvement in Behçet’s disease. Clin Exp Rheumatol. 2006;24(5 Suppl 42):S65-70.

  25. Al-Araji A, Kidd DP. Neuro-Behçet’sdisease: epidemiology, clinicalcharacteristics, and management. Lancet Neurol. 2009; 8:192-204.

  26. Diri E, Espinoza LR. Neuro-Behçet’s Syndrome: Differential Diagnosis and Management. Current Rheumatology Reports. 2006; 8:317-22.

  27. Martínez Larrarte José Pedro, Cepero Morales Raúl, Sosa Almeida Mirtha, Molinero Rodríguez Claudino, Lantigua Martell María A.. Síndrome de Behcet: Presentación de un caso. Rev cubana med [Internet]. 1998 Dic [citado 2015 Jul 23];37(4):249-52. Disponible en: http://scieloprueba.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75231998000400007&lng=es

  28. Mohamed C, Najib K, Essaadouni L. Radiological findings in Behçet disease. Pan African Medical Journal. 2015;20(1). doi: 10.11604/pamj.2015.20.51.5928.

  29. Afshin B, Sirous S, Siamak F. MRI findings of neuro-Behcet’s disease. Clin Rheumatol. 2011; 30:765-70. doi: 10.1007/s10067-010-1650-9.

  30. Noel N, Hutie M, Wechsler B, Vignes S, Huong-Boutin DLT, Amoura Z et al. Pseudotumoural presentation of neuro-Behçet’sdisease: case series and review of literature. Rheumatology. 2012;51:1216-25. doi:10.1093/rheumatology/ker449.

  31. Martins W, Schilling L, Neto F, Becker J. Hypertrophic Olivary Degeneration Secondary to Neuro-Behçet’sDisease. Clin Neuroradiol. 2015. doi: 10.1007/s00062-015-0384-0.

  32. Akman-Demir G, Tuzun E, İçöz, S, Yeşilot N, Yentü SP, Kürtüncü M, Saruhan-Direskeneli G. Interleukin-6 in neuro-Behçet’s disease: association with disease subsets and long-term outcome. Cytokine. 2008; 44:373-6.

  33. Fonseca CardosoA, Rocha-Filho PA, Melo Correa-LimaAR. Neuro-Behçet: differential diagnosis of recurrent meningitis. Rev Med Chile. 2013;141:114-8.

  34. Haghighi AB, Safari A. Proposing an algorithm for treatment of different manifestations of neuro-Behcet’s disease. Clin Rheumatol. 2010; 29:683-6. doi: 10.1007/s10067-010-1414-6.

  35. Arida A, Fragiadaki K, Giavri E, Sfikakis PP. Anti-TNF agents for Behçet’s disease: analysis of published data on 369patients. Semin Arthritis Rheum. 2011; 41:61-70.

  36. Akman-Demir G, Saip S, Siva A. Behçet’s Disease. Current Treat Options in neurology. 2011; 13:290-310.

  37. Mora P, Menozzi C, Orsoni JG, Rubino P, Ruffini L, Carta A. Neuro-Behçet’s disease in childhood: A focus on the neuro-ophthalmological features. Orphanet Journal of Rare Diseases. [Internet]. 2013 [citado 2015 Jul 23]; 8:18. Disponible en: http://www.biomedcentral.com/content/pdf/1750-1172-8-18.pdf

  38. Uluduz D, Kurtuncu M, Yapici Z, Seyahi E, Kasapçopur Ö, Özdoğan H, Siv, A. Clinical characteristics of pediatric onset neuro- Behçet‘s disease. Neurology. 2011,77(21):1900-5.

  39. Ostensen M, Ramsey-Goldman R. Treatment of Inflammatory Rheumatic Disorders in Pregnancy. What are the Safest Treatment Options? Drug Safety. [Internet].1998 [citado 2015 Jul 29];19(5):389-410. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/9825952

  40. Marsal S, Falga C, Simeon CP, Vilardell M, Bosch JA. Behçet’s disease and pregnancy relationship study. Br J Rheumatol. [Internet]. 1997 [citado 2015 Jul 29];36(2):234-8. Disponible en: http://rheumatology.oxfordjournals.org/content/36/2/234.full.pdf




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