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2015, Number 4

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Rev Cubana Pediatr 2015; 87 (4)

Behavior of non-Hodgkin lymphoma at pediatric ages

Verdecia CC, Santos LME, Lam DRM

Language: Spanish
References: 16
Page: 460-467
PDF size: 141.70 Kb.


ABSTRACT

Introduction: non-Hodgkin lymphomas are frequent hematological neoplasias in infancy.
Objective: to describe the different forms of presentation of this disease at the pediatric age and to determine the average years lived after the treatment.
Methods: a retrospective and descriptive study of 79 patients was conducted; they had been diagnosed as non-Hodgkin lymphoma cases and attended to at the oncologic surgery service of “William Soler” pediatric teaching hospital from March 1995 to March 2014.
Results: forty eight patients were males and 31 were females. The most affected age group was the 10-14 years-old one. In the group, 54.4 % of patients had lymphomas located in the abdominal region and 29.1 % in the mediastinal location. Other affected areas were cervical region, palatal tonsil and primary renal region in 10.1 %, 3.8 % and 2.6 % of patients, respectively. The most common histological variant was immunophenotype B non-Hodgkin lymphoma (75.9 %) followed by immunophenotype T non-Hodgkin lymphoma (21.5 %). Abdominal pain and palpable tumor mass was the main clinical manifestation in 64.5 % of cases. The average life years in non-Hodgkin lymphoma located in the renal region, cervical region and palatal tonsil was slightly higher (5.7 ± 0.3, 5.5 ± 1.8 and 5.2 ± 0.7, respectively).
Conclusions: the immunophenotype B non-Hodgkin lymphoma of abdominal location is the most common. Abdominal pain and tumors are the main clinical manifestations and the patients with non-Hodgkin lymphomas in the cervical region and the palatal tonsil show higher average life years after treatment.


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