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2002, Number 4

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Rev Inst Nal Enf Resp Mex 2002; 15 (4)

Larynx cancer. Experience at the National Oncology Institute. La Habana, Cuba. 1966-1996.

Díaz MJR, López CRI, Lugo AJ, Rodríguez SC, Cuevas PI
Full text How to cite this article

Language: Spanish
References: 8
Page: 220-225
PDF size: 55.62 Kb.


Key words:

Cancer of the larynx, topographic location, deceased, multiple tumors, treatment.

ABSTRACT

Objective: To determine the main clinical, pathological and anatomical characteristics of the lesions of patients with initial diagnosis of larynx cancer; and the treatment, survival and causes of death of deceased patients treated at the National Oncology Institute of La Habana, Cuba, between 1966 and 1996. Material and methods: The clinical records of 630 patients with presumptive diagnosis of cancer of the larynx, deceased at the National Oncology Institute in Havana, between 1966 and 1996 were examined. Results: The supraglottic and glottic larynx assembled the largest amount of deceased patients with 238 and 208 cases respectively, which represents 70.79%. The largest evaluated group was included in the classification T3N0 with 158 patients that totaled 25.07%, followed by T1N0 with 118 patients, or 18.73%. Radiotherapy with Co60 was used in 398 patients, 63.17%, and surgery in 139 patients, 22.06%, the combination of radiotherapy and chemotherapy was used in only 21 cases (3.33%). The presence of multiple tumors was diagnosed in 73 patients, 11.58%, and the main locations were: lung, bladder, tonsil and prostate. A total of 222 patients, 35.23%, died during the first year after diagnosis, 61.11% in the first two years, and only 15.39% of the patients died after the 5th year. Recurrence diagnosis was performed during the first year in 421 (66.82%) and it reappeared after five years in only in 58 cases (9.20%). Conclusions: The largest number of patients died due to the primary tumor, 473 cases, and 33 patients died due to complications of surgical procedures.


REFERENCES

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  2. Díaz MJR, Rodríguez BO, Thompson LJL, Lugo AJ. Fallecidos por carcinoma faríngeo. 1966-1996. Oncología 2001;24:446-451.

  3. Kowalsky LP, Batista M, Santos CR, Scopel A, Salcajolli JV, Torloni H. Prognostic factors in T3, N0–1 glottic and transglottic carcinoma. Arch Otolaryngol Head Neck Surg 1996;122:77-82.

  4. Herranz J, Fernández M, Ramos S, Martínez VJ, Gavilán J, Gavilán C, y cols. Radioterapia en carcinoma glótico T1. Control local y sobrevida. Acta Otorrinolaringol Esp 2000;51:57-61.

  5. Martínez-Berganza R, De Miguel GF, Fraile RJJ, Gil PP, Naya MJ. Mortalidad en cirugía por cáncer laríngeo. Acta Otorrinolaringol Esp 1998;49:206-210.

  6. Díaz MJR. Carcinoma laríngeo: incidencia en el Instituto Nacional de Oncología en 10 años (1981-1990). Oncología SOLCA 1997;7:102-104.

  7. Kajanti MJ, Holsti LR. Radical surgery and postoperative split-course radiotherapy in squamous cell carcinoma of the head and neck. Factors influencing local control and survival. Acta Oncol 1993;32:319-325.

  8. Berrino F, Gatta G. Variation in survival of patients with head and neck cancer in Europe by site of origin of the tumours. Eur J Cancer 1998;34:2154-2161.




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Rev Inst Nal Enf Resp Mex. 2002;15