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2016, Number 1

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Rev Med Inst Mex Seguro Soc 2016; 54 (1)

Effectiveness of the outpatient treatment of the community-acquired pneumonia: systematic review and meta-analysis

Castelán-Martínez OD, Hernández-Carbajal E, Contreras-García CE, Guadalupe-Ojeda LN, Rivas-Ruiz R

Language: Spanish
References: 29
Page: 128-136
PDF size: 319.46 Kb.


ABSTRACT

Background: Community-acquired pneumonia is an important cause of mortality and morbidity worldwide. Therefore, our aim was to assess the efficacy and safety of outpatient treatment of community-acquired pneumonia.
Methods: We systematically reviewed randomized clinical trials evaluating efficacy and safety of outpatient treatment (OPT) compared with inpatient treatment (IPT) of community-acquired pneumonia in patients without added co-morbidity. Relative Risk (RR) and 95 % confidence interval (95 % CI) were calculated.
Results: From 4088 reviewed articles, two articles were included for meta-analysis, including 2324 patients. One study was conducted in adults, and the other was carried out in pediatric patients. Treatment setting was not significantly associated with treatment failure (RR 0.84 [95% CI 0.68, 1.02]). Death occurred in 6 of 2324 with no difference between the two groups (RR 0.56 [95 % CI 0.12-2.61]). Finally, no differences were seen in hospital readmission between groups (RR 0.82 [95 % CI 0.52-1.30]).
Conclusion: Evidence shows that treatment setting of communityacquired pneumonia is not statistically associated with treatment failure or mortality.


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