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2015, Number 2

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Rev Med MD 2015; 6.7 (2)

Serotoninergic syndrome caused by linezolid and metoclopramide: a case report

Viesca-Contreras V

Language: Spanish
References: 11
Page: 96-100
PDF size: 575.22 Kb.


ABSTRACT

Serotoninergic syndrome occurs when serotonin levels increase within the central nervous system. It is an unfavorable reaction resulting from the interaction between medications that increase the activity of serotoninergic neurotransmission in the central and peripheral nervous system. This is an unpopular and sometimes deadly medical emergency.
The syndrome's identification may be challenging and is often ignored by many physicians, since clinical manifestations not specific. Its incidence has recently increased due to the extensive use of drugs associated to this entity. Serotoninergic syndrome is often iatrogenic and it can only be modified if the physician is aware of its existence. Symptoms may disappear when the causing drug is withdrawn and support treatment is started. This syndrome is characterized by a triad involving alterations in mental state, neuromuscular and autonomic dysfunction. We present the case of a 36 year old woman who after abdominal surgery and a series of complications developed this syndrome.


REFERENCES

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