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Órgano Oficial de la Asociación Mexicana de Hepatología

2016, Number 1

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Ann Hepatol 2016; 15 (1)

Reply to contribution on the topic of hypovitaminosis D in chronic hepatitis C

Villar LM, Lampe E, de Almeida AJ, Scalioni LP, Lewis-Ximenez LL, Custódio MJ, Del Campo JA, Ranchal I, Villela-Nogueira CA, Romero-Gomez M

Language: English
References: 7
Page: 139-140
PDF size: 100.74 Kb.


Text Extraction

To The Editor,
We would like to thank Basyigit, et al. for their comments of on our recent study that aimed to determine pretreatment 25(OH)D serum level among hepatitis C virus (HCV) infected individuals and its impact on virological response and laboratory data. Our main results were hepatitis C patients showed lower vitamin D level and it was associated to laboratory findings; however baseline 25(OH)D level was not independently associated with sustained virological response (SVR).


REFERENCES

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  2. Lange CM, Bojunga J, Ramos-Lopez E, von Wagner M, Hassler A, Vermehren J, Herrmann E, et al. Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferon-alfa based therapy. J Hepatol 2011; 54: 887-93.

  3. Falleti E, Cmet S, Fabris C, Fattovich G, Cussigh A, Bitetto D, Ceriani E, et al. Genetic polymorphisms of vitamin D pathway predict antiviral treatment outcome in slow responder naïve patients with chronic hepatitis C. PLoS One 2013; 8(11): e80764.

  4. Villar LM, Del Campo JA, Ranchal I, Lampe E, Romero-Gomez M. Association between vitamin D and hepatitis C virus infection: a meta-analysis. World J Gastroenterol 2013; 19: 5917-24.

  5. Rahman AH, Branch AD. Vitamin D for your patients with chronic hepatitis C? J Hepatol 2013; 58: 184-9.

  6. Bitetto D, Fabris C, Fornasiere E, Pipan C, Fumolo E, Cussigh A, Bignulin S, et al. Vitamin D supplementation improves response to antiviral treatment for recurrent hepatitis C. Transpl Int 2011; 24: 43-50.

  7. Kitson MT, Sarrazin C, Toniutto P, Eslick GD, Roberts SK. Vitamin D level and sustained virologic response to interferonbased antiviral therapy in chronic hepatitis C: a systematic review and meta-analysis. J Hepatol 2014; 61: 1247-52.




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