2011, Number 4
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Ann Hepatol 2011; 10 (4)
Cholestasis as the initial presentation of relapsing polychondritis
da Graça FM, Jönck SL, Teixeira PVRC, da Rosa L, Cacese SMB, Narciso-Schiavon JL, Dantas-Correa EB, de Lucca SL
Language: English
References: 10
Page: 565-567
PDF size: 561.69 Kb.
ABSTRACT
Relapsing polychondritis is an immune-mediated disease associated with inflammation in cartilaginous structures
and other tissues throughout the body, particularly the ears, nose, eyes, joints, and respiratory
tract. Although association with other conditions is seen in about one-third of the cases, liver involvement
is not usually observed in those patients. We described a case of liver involvement in relapsing polychondritis,
presenting with a predominantly cholestatic pattern. Other conditions associated with abnormal liver
tests were excluded and the patient showed a prompt response to steroid therapy. We discuss the
spectrum of the liver involvement in relapsing and review the literature.
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