Hardt CC, Conforti RB, Garcia R, Garcia A

Language: Spanish
References: 12
Page: 145-148
PDF size: 325.68 Kb.

ABSTRACT

Chronic ulcers are a frequent reason of daily consultation and incapacitating. They preoccupied the patient, its family and the physician. Autologous rich platelets plasma is a simple and low cost option for the treatment of this pathology. We present a 61 old male patient, with diabetic ulcers in both legs of difficult management. Complete resolution is achieved using autologous rich platelets plasma.

REFERENCES

1. Lacci KM, Dardik A. Platelet-Rich plasma: support for its use in wound healing. Yale J Biol Med. 2010; 83: 1-9.

2. Jiménez V, Espinola M, Láinez SA, Matas H, Nieto M, Rodríguez J et al. Tratamiento local de úlceras por presión. Bol Ter Andal. 2000; 16(5): 17-20.

3. Monclús Fuertes E, Velasco Velasco R, Gómez- Escolar Larrañaga L, González Peirona, E. Nuestra experiencia en el tratamiento de úlceras crónicas mediante PRF- Vivostat®. Serie de 10 casos. Cir Plást Iberolatinoam. 2009; 35 (2): 141-148.

4. Bernuzzi G, Tardito S, Bussolati O, Adorni D, Cantarelli S, Fagnoni F et al. Platelet gel in the treatment of cutaneous ulcers: the experience of the Inmunohaematology and Transfusion Centre of Parma. Blood Transfus. 2010; 8: 237-247.

5. Beca T, Hernández G, Morantes S, Bascones A. Plasma rico en plaquetas. Una revisión bibliográfica. Av Periodon Implantol. 2007; 19 (1): 39-52.

6. Montón EJ, Pérez RS, Gómez BGJ. Experiencia clínica en el empleo de factores de crecimiento autólogos obtenidos de plasma rico en plaquetas. Cir Plást Iberolatinoam. 2007; 33 (3): 155-162.

7. Scimeca CL, Bharara M, Fisher T, Kimbriel H, Armstrong D. Novel use of platelet-rich plasma to augment curative diabetic foot surgery. J Diabetes Sci Technol. 2010; 4 (5): 1121-1126.

8. Chen L, Wang C, Liu H, Liu G, Ran X. Antibacterial effect of autologous platelet-rich gel derived from subjects with diabetic dermal ulcers in vitro. J Diabetes Res. 2013; 2013: 269527.

9. Giusti I, Rughetti A, Dáscenzo S, Millimaggi D, Pavan A, Dell´Orso L et al. Identification of an optimal concentration of platelet gel for promoting angiogenesis in human endotelial cells. Transfusion. 2009; 49 (4): 771-778.

10. Frykberg R, Driver V, Carman D, Borris-Hale C, FyllingC, Rappl L et al. Chronic wounds treated with physiologically relevant concentration of platelet rich plasma gel: a prospective case series. Ostomy Wound Manage. 2010; 56 (6): 36-44.

11. Tzeng YS, Deng SC, Wang CH, Tsai JC, Chen TM, Burnouf T. Treatment of nonhealing diabetic lower extremity ulcers with skin graft and autologous platelet gel: a case series. Biomed Res Int. 2013; 2013: 837620.

12. Krupski WC, Reilly LM, Perez S, Moss KM, Crombleholme PA, Rapp JH. A prospective randomized trial of autologous platelet-derived wound healing factors for treatment of chronic nonhealing wounds: a preliminary report. J Vasc Surg. 1991; 14 (4): 526-532; discussion 532-6.