Ekiz F, Yüksel I, Ekiz Ö, Coban S, Basar Ö, Yüksel O

Language: English
References: 3
Page: 237-238
PDF size: 24.62 Kb.

Text Extraction

Dear Editor
Levocetirizine is a third-generation non-sedative antihistaminic agent and has developed from the second- generation antihistaminic drug: cetirizine. It may have side effects such as sleepiness, headache, dry mouth, lightheadedness, vision problems, palpitations and fatigue. There are only few cases reporting cetirizine induced liver toxicity. However, we could not find any published data about levocetirizine associated hepatotoxicity in the literature. Herein, we present the first case of levocetirizine induced hepatotoxicty.

REFERENCES

1. Pasquali M, Baiardini I, Rogkakou A, Riccio AM, Gamalero C, Descalzi D, et al. Levocetirizine in persistent allergic rhinitis and asthma: effects on symptoms, quality of life and inflammatory parameters. Clin Exp Allergy 2006; 36: 1161-7.

2. Pompili M, Basso M, Grieco A, Vecchio FM, Gasbarrini G, Rapaccini GL. Recurrent acute hepatitis associated with use of cetirizine. Ann Pharmacother 2004; 38: 1844-7.

3. Assis DN, Navarro VJ. Human drug hepatotoxicity: a contemporary clinical perspective. Expert Opin Drug Metab Toxicol 2009; 5: 463-73.