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ISSN 1561-3011 (Electronic)

2015, Number 4

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Rev Cubana Invest Bioméd 2015; 34 (4)

Composition of urolithiasis in Cuban patients by sex

Bacallao MRA, Mañalich CR, Gutiérrez GF, Badell MA

Language: Spanish
References: 17
Page: 328-336
PDF size: 140.47 Kb.


ABSTRACT

Introduction: urolithiasis imply significant morbidity and economic costs. For its management, it is fundamental to make clinical and lab evaluation including the study of the chemical composition.
Objective: to determine the frequency of occurrence of several types of urolithiasis according to their composition and relationship with the individual’s sex.
Methods: descriptive and cross-sectional study that included urolithiasis of Cuban adults sent to the Renal Physiopathology Lab of the Institute of Nephrology for the study of chemical composition in the 2001-2011 period. A Philips PU9516 infrared spectroscope served to analyze lithiasis. The various compounds were identified by comparing them with the reference spectra. All the data were collected and processed with SPSS 15.0; the frequency distribution analysis. Independence test and Fisher’s exact test were used to confirm the differences between sexes in terms of type of lithiasis.
Results: of 1815 analyzed lithiasis, 1316 (71.1 %) were simple. Simple calcium oxalate lithiasis represented 46.8 % of the total number. In the combinations, the most frequent were calcium oxalate plus calcium phosphate (24.7 %). The frequency of calcium oxalate and uric acid lithiasis was higher in men (p= 0.00 and those of calcium phosphate and struvite (p= 0.00) in women.
Conclusions: calcium stones, mainly monohydrated calcium oxalate, are the most common in the studied lithiatic population. Calcium oxalate and uric acid are the commonest in men whereas struvite and calcium phosphate are more frequent in women.


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