2005, Number 12
Ginecol Obstet Mex 2005; 73 (12)
Prevalence of Streptococcus agalactiae colonization in pregnant women at term
Romero GG, Pacheco LG, García OJ, Horna LA, Ponce PDAL, Vargas OA
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To determine the prevalence of colonization by Streptococcus agalactiae in pregnant women at term.
Material and methods:
We carried out a cross-sectional study. Four hundred thirty three pregnant patients at term without data of cervicovaginitis were included. We processed vaginal and rectal swabs with hisopo placed in the Stuart middle of transport. They were inoculated on blood agar with nalidixic acid and gentamicine incubating itself by duplicate on Todd-Hewitt broth. The samples with suggestive result were reincubating to detect suspicious Streptococcus using the CAMP test, for final identification. Some clinical variables were included as age, gravidity, parity, abortions, cesarean sections, and vaginal infections during pregnancy.
We found two patients with positive result for Streptococcus agalactiae in vaginal swabs that represented a prevalence of 0.46%; in those cases therapeutic measures were provided for both mother and newborn. The mean age for patients was 27 years. The median value for gravidity was 2, for parity was 1; and for spontaneous abortions and cesarean sections were 0, respectively. In our studied women 77.8% of them referred previous unspecified vaginal infections.
In our setting the prevalence of Streptococcus agalactiae colonization in pregnant women at term is low. Due to morbidity associated to this infection, it is suggested the specific research of this microorganism both in pregnant women and in their newborns.
Regan JA, Klebanoff MA, Nugent RP, Eschenbach DA, et al. Colonization with group B streptococci in pregnancy and adverse outcome. VIP Study Group. Am J Obstet Gynecol 1996;174:1354-60.
Grable IA, García PM, Perry D, Socol ML. Group B Streptococcus and preterm premature rupture of membranes: a randomized, double-blind clinical trial of antepartum ampicilin. Am J Obstet Gynecol 1996;175:1036-42.
Silver HM, Struminsky J. A comparison on of the yield of positive antenatal group B Streptococcus cultures with direct inoculation in selective growth medium versus primary inoculation in transport medium followed by delayed inoculation in selective growth medium. Am J Obstet Gynecol 1996;175:155-7.
Factor SH, Levine OS, Nassar A, Potter J, et al. Impact of a risk based prevention policy on neonatal group B Streptococcal disease. Am J Obstet Gynecol 1998;179:1568-71.
Baker CJ, Edwards MS. Group B streptococcal infections. Perinatal impact and prevention methods. Ann N Y Acad Sci 1998;549:193-202.
Motlova J, Strakova L, Urbaskova P, Sak P, Sever T. Vaginal and rectal carriage of Streptococcus agalactiae in the Czech Republic: incidence, serotypes, distribution and susceptibility to antibiotics. Indian J Med Res 2004;119:84-7.
Solórzano-Santos F, Díaz-Ramos RD, Arredondo-García JL. Diseases caused by group B streptococcus in Mexico. Pediatr Infect Dis J 1990;9:66.
Dillon HC Jr, Khare S, Gray BM. Group B Streptococcal carriage and disease: a 6–year prospective study. J Pediatr 1987;110:31-6.
Remington JS, Klein JO. Infectious diseases of the fetus and newborn infant. Philadelphia: Saunders, 1995;p:980.
Gibbs RS, Schrag S, Schuchat A. Perinatal infection due to group B streptococci. Obstet Gynecol 2004;104:1062-76.
Barbaros I, Murat C, Mehmet V, Ali Ismet T, et al. The colonization incidence of group B streptococcus in pregnant women and their newborns in Istanbul. Pediatr Inter 2005;47:64-6.
García SD, Eliseth MC, Lazz MJ, Copolillo E, et al. Group B Streptococcus carriers among pregnant women. Rev Argent Microbiol 2003;35:183-7.
Carrasco-Morales I, Reyna-Figueroa J, Beltran-Zuñiga M, Segura-Cervantes E, et al. Perfil clínico y demográfico de pacientes con patología gineco-obstétrica colonizadas por Streptococcus agalactiae. Ginec Obstet Mex 2002;70:521-26.
Solórzano-Santos F, Arredondo-García JL, Ortiz-Ibarra FJ, Díaz-Ramos RD, et al. Streptococcus del grupo B en la etiología de la infección neonatal. Bol Med Hosp Infant Mex 1990;47:146-51
Ali Z. Neonatal bacterial septicaemia at the Mount Hope Women’s Hospital Trinidad. Ann Trop Paediatr 2004; 24: 41-4.
Trijbels-Smeulders M, Kollee LA, Adriaanse A, Kimpen J, Gerards L. Neonatal group B streptococcal infection: incidence and strategies for prevention in Europe. Pediatr Infec Dis J 2004;23:172-3.