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ISSN 0001-0944 (Print)
Órgano Oficial de la Asociación Dental Mexicana

2016, Number 2

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Rev ADM 2016; 73 (2)

Evaluation of periodontal disease and hyperglycemia associated to type 2 diabetes mellitus in patients of Durango State, Mexico

Peralta-Álvarez D, Espinosa-Cristóbal LF, Carreón-Burciaga RG, Bologna-Molina R, González-González R, Gómez-Palacio-Gastelum M, Donohué-Cornejo A

Language: Spanish
References: 28
Page: 72-80
PDF size: 201.77 Kb.


ABSTRACT

Background: Diabetes mellitus is considered a public health problem worldwide and one that affects organs and systems alike, including the oral cavity. However, there are few reports in the literature on the effects of diabetes mellitus on the oral cavity of the population in the north of Mexico. Objective: The aim of this study was to determine the link between various oral diseases, body mass index, and blood glucose level in patients with diabetes mellitus. Material and methods: A case-control study was conducted to identify the prevalence of oral diseases in patients with and without diabetes mellitus. Patients with type 1 or type 2 diabetes mellitus were defined as cases and patients with other diseases were defined as controls. The body mass index and blood glucose concentration of all subjects were measured. Statistical analysis included chi-squared tests, and the average and standard deviation of the data. Results: 312 subjects were assessed: 38 patients with type 1 diabetes mellitus, 79 with type 2 diabetes mellitus, and 195 without diabetes mellitus. Significant differences were found in DM2 patients, who were more likely to exhibit periodontitis and high blood glucose levels. Furthermore, the presence of obesity and hypertension in patients with type 2 diabetes was found to be a risk factor for developing periodontitis. Conclusions: Type 2 diabetes mellitus may be a risk factor for periodontal disease, while the level of hyperglycemia increased the likelihood of a DM2 patient suffering from periodontitis if he or she also suffered from obesity and hypertension.


REFERENCES

  1. Murrah VA. Diabetes mellitus and associated oral manifestations: a review. J Oral Pathol. 1985; 14 (4): 271-281.

  2. Bharateesh J, Ahmed M, Kokila G. Diabetes and oral health: a case-control study. Int J Prev Med. 2012; 3 (11): 806-809.

  3. Ramavat PR, Ramavat MR, Ghugare BW, Vaishnav RG, Joshi MU. Prevalence of diabetic retinopathy in Western Indian type 2 diabetic population: a hospital-based cross-sectional study. J Clin Diagn Res. 2013; 7 (7): 1387-1390.

  4. Villegas PA, Abad SB, Faciolince S, Hernández N, Maya C, Parra L et al. Controlling diabetes mellitus and its complications in Medellín, Colombia, 2001-2003. Rev Panam Salud Publica. 2006; 20 (6): 393-402.

  5. Instituto Nacional de Salud Pública. Encuesta Nacional de Salud y Nutrición 2012. Resultados Nacionales. Secretaría de Salud. 2012; 1: 127-180.

  6. Genuth S, Alberti KG, Bennett P, Buse J, Defronzo R, Kahn R et al; Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care. 2003; 26 (11): 3160-3167.

  7. Stopford R, Winkley K, Ismail K. Social support and glycemic control in type 2 diabetes: A systematic review of observational studies. Patient Educ Couns. 2013; 93 (3): 549-558.

  8. Miranda Galvis M, Montoya Zuluaga YP, Saldarriaga Saldarriaga A. Diabetes y enfermedad periodontal: hacia un modelo clínico bidireccional. Rev Nal OdoUCC. 2012; 8 (14): 76-85.

  9. Young BA, Lin E, Von Korff M, Simon G, Ciechanowski P, Ludman EJ et al. Diabetes complications severity index and risk of mortality, hospitalization, and healthcare utilization. Am J Manag Care. 2008; 14 (1): 15-23.

  10. Iacopino AM. Periodontitis and diabetes interrelationships: role of inflammation. Ann Periodontol. 2001; 6 (1): 125-137.

  11. Pradeepa R, Mohan V. The changing scenario of the diabetes epidemic: implications for India. Indian J Med Res. 2002; 116: 121-132.

  12. Kiran M, Arpak N, Unsal E, Erdoğan MF. The effect of improved periodontal health on metabolic control in type 2 diabetes mellitus. J Clin Periodontol. 2005; 32 (3): 266-272.

  13. American Diabetes Association. Standards of medical care in diabetes—2010. Diabetes Care. 2010; 33 (Suppl 1): S11-61.

  14. Narang R, Saha S, G V J, Kumari M, Mohd S, Saha S. The maternal socioeconomic status and the caries experience among 2-6 years old preschool children of Lucknow City, India. J Clin Diagn Res. 2013; 7 (7): 1511-1513.

  15. Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA. 2010; 303 (3): 235-241.

  16. Cornier MA, Després JP, Davis N, Grossniklaus DA, Klein A, Lamarche B et al. Assessing adiposity: A scientific statement from the American Heart Association. Circulation. 2011; 124 (18): 1996-2019.

  17. Trinder P. Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen. J Clin Pathol. 1969; 22 (2): 158-161.

  18. Friedman and Young. Effects of disease on clinical laboratory tests. 3rd ed. AACC Press; 1997.

  19. Salcedo-Rocha AL, Sánchez-Mar M, López-Pérez Mde L, Preciado-Soltero HT, Figueroa-Suárez PA, Narváez-Aguirre VA et al. Oral signs in patients with type-2 diabetes, hypertension and obesity. Rev Med Inst Mex Seguro Soc. 2006; 44 (3): 203-210.

  20. Apoorva SM, Sridhar N, Suchetha A. Prevalence and severity of periodontal disease in type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus) patients in Bangalore City: An epidemiological study. J Indian Soc Periodontol. 2013; 17 (1): 25-29.

  21. Patiño MN, Loyola RJP, Medina SCE, Pontigo LAP, Reyes MJF, Ortega RJC et al. Caries, periodontal disease and tooth loss in patients with diabetes mellitus types 1 and 2. Acta Odontol Latinoam. 2008; 21 (2): 127-133.

  22. Kim J, Amar S. Periodontal disease and systemic conditions: a bidirectional relationship. Odontology. 2006; 94 (1): 10-21.

  23. Mealey BL. Periodontal disease and diabetes. A two-way street. J Am Dent Assoc. 2006; 137 (Suppl): 26S-31S.

  24. Grossi SG, Skrepcinski FB, DeCaro T, Robertson DC, Ho AW, Dunford RG et al. Treatment of periodontal disease in diabetics reduces glycated hemoglobin. J Periodontol. 1997; 68 (8): 713-719.

  25. Mealey BL, Rethman MP. Periodontal disease and diabetes mellitus. Bidirectional relationship. Dent Today. 2003; 22 (4): 107-113.

  26. Grossi SG, Genco RJ. Periodontal disease and diabetes mellitus: a two-way relationship. Ann Periodontol. 1998; 3 (1): 51-61.

  27. Bajaj S, Prasad S, Gupta A, Singh VB. Oral manifestations in type-2 diabetes and related complications. Indian J Endocrinol Metab. 2012; 16 (5): 777-779.

  28. Saremi A, Nelson RG, Tulloch-Reid M, Hanson RL, Sievers ML, Taylor GW et al. Periodontal disease and mortality in type 2 diabetes. Diabetes Care. 2005; 28 (1): 27-32.




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