2015, Number 6
Rev Invest Clin 2015; 67 (6)
Altitude Above Sea Level and Body Mass Index as Determinants of Oxygen Saturation in Children: The SON@ Study
Gochicoa-Rangel L, Pérez-Padilla R, Rodríguez-Moreno L, Montero-Matamoros A, Ojeda-Luna N, Martínez-Carbajal G, Hernández-Raygoza R, Ruiz-Pedraza D, Fernández-Plata MR, Torre-Bouscoulet L
PDF size: 938.03 Kb.
ABSTRACTBackground: Altitude above sea level and body mass index are well-recognized determinants of oxygen saturation in adult populations; however, the contribution of these factors to oxygen saturation in children is less clear. Objective: To explore the contribution of altitude above sea level and body mass index to oxygen saturation in children. Methods: A multi-center, cross-sectional study conducted in nine cities in Mexico. Parents signed informed consent forms and completed a health status questionnaire. Height, weight, and pulse oximetry were recorded. Results: We studied 2,200 subjects (52% girls) aged 8.7 3.0 years. Mean body mass index, z-body mass index, and oxygen saturation were 18.1 ± 3.6 kg·m-2, 0.58 ± 1.3, and 95.5 ± 2.4%, respectively. By multiple regression analysis, altitude proved to be the main predictor of oxygen saturation, with non-significant contributions of age, gender, and body mass index. According to quantile regression, the median estimate of oxygen saturation was 98.7 minus 1.7% per km of altitude above sea level, and the oxygen saturation fifth percentile 97.4 minus 2.7% per km of altitude. Conclusions: Altitude was the main determinant of oxygen saturation, which on average decreased 1.7% per km of elevation from a percentage of 98.7 at sea level. In contrast with adults, this study in children found no association between oxygen saturation and obesity or age.