Espadas-Villaseñor M, Pérez-González A, Macías-Chumacera A, Cerpa-Cruz S, Jiménez-Cázarez MB, Bazzini-Carranza DE, Polanco-Cruz J, Arroyo-Prado I, Gómez-López CE, González-Díaz V, Martínez-Bonilla G, Esturau-Sotale R, Cardona-Muñoz EG,Cardona-Muller D, Alanis-Sánchez A, Gutiérrez-Ureña S, De la Cruz-Rodríguez KI

Language: Spanish
References: 10
Page: 149-154
PDF size: 627.33 Kb.

ABSTRACT

Introduction: Systemic sclerosis is a connective tissue disease of unknown etiology. There are two main mechanisms: microvasculopathy and fibrosis. Arterial rigidity is an important cardiovascular risk factor in this type of patients. Evaluation is done using non-invasive methods such as peripheral and central augmentation index, pulse wave velocity and central systolic pressure.
Material and Method: This is a transversal study including outpatients diagnosed with systemic sclerosis, >18 years old attending the rheumatology unit at Hospital Civil “Fray Antonio Alcalde” from June 2015 to November 2015. The main objective was to evaluate arterial rigidity using noninvasive methods.
Results: There was a total amount of 20 patients with systemic sclerosis, 100% of them women. The pulse wave velocity was measured in 16 patients with an average speed of 7.5 m/sec. Two patients had pulse wave velocity >10 m/sec. We found that average central systolic pressure in our patients was greater in every age group except in those from 50 to 59 years old. 50% of our patients with systemic sclerosis have values above the normal range, which can be interpreted as arterial rigidity.
Conclusion: 50% of the population studied has at least one value indicating an increase in arterial rigidity according to age. The central augmentation index is positively associated to the time since systemic sclerosis diagnosis, which had not been previously described.

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