Amieva-Balmori M, Azamar-Jácome AA, Rojas-Carrera SI, Cano-Contreras AD, Remes-Troche JM

Language: Spanish
References: 29
Page: 161-168
PDF size: 671.24 Kb.

ABSTRACT

Background: Up to one third of cholecystectomized patients develop new symptoms after surgery, such as abdominal pain, flatulence and diarrhea. There is controversy about this is a result of bile salt absorption. The risk to develop irritable bowel syndrome (IBS) after cholecystectomy is 2.2 times higher than in general population.
Objetive: To evaluate the prevalence of IBS and its subtypes (according to Rome III criteria) in a group of patients with a history of cholecystectomy compared with a control group.
Material and Method: An observational, comparative, crosssectional and retrospective study in which patients were assessed about sociodemographic data, history of cholecystectomy and symptoms consistent with IBS according to Rome III criteria.
Results: 345 patients (251 women and 94 men, mean age 45.5±15.3 years) were distributed into two groups: group 1 (n=77), subjects with a history of cholecystectomy or biliary disease, and group 2 (n=268) control subjects. The prevalence of IBS was 54% in group 1 and 23% in group 2 (p‹0.001, OR 3.67, 95% CI 2.64-5.24). Subjects in group 1 had higher frequency of IBS-D subtype (36% vs 15%, p=0.01, OR 2.9, 95% CI 2.34-4.47) and showed more loose stools (p=0.001).
Conclusion: In our study, the prevalence of IBS in cholecystectomy patients was 3.6 times higher than in control group, the IBS-D subtype was the most prevalent.

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