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2016, Number 2

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Med Int Mex 2016; 32 (2)

Hypoparathyroidism and Graves disease. A rare association

Del Río-Prado AF, González- López JA
Full text How to cite this article

Language: Spanish
References: 10
Page: 244-248
PDF size: 533.26 Kb.


Key words:

hypocalcemia, hyperphosphatemia, parathyroid hormone, hyperthyroidism.

ABSTRACT

This paper reports the case of a 26-year-old female patient that during postpartum presented generalized seizures and muscle spams associated with severe hypocalcemia and hyperphosphatemia with inappropriately low levels of parathyroid hormone (PTH). In the evaluation it was detected autoimmune hyperthyroidism that required definitive management with radioactive iodine and levothyroxine replacement.


REFERENCES

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  2. Cutolo M. Autoimmune polyendocrine syndromes. Review. Autoimmun Rev 2014;13:85-89.

  3. Wémeau JL, Proust-Lemoine E, Ryndak A, Vanhove L. Thyroid autoimmunity and polyglandular endocrine syndromes. Review. Hormones 2013;12:39-45.

  4. Lebovitz H. Autoimmune polyglandular syndromes: Interplay between the immune and the endocrine systems leading to a diverse set of clinical diseases and new insights into immune regulation. Diab Technol Ther 2013;15(Suppl 2).

  5. Shoback D. Hypoparathyroidism. Clinical Practice. NEJM 2008;359:391-403.

  6. Bilezikian J, Khan A, Potts J, Brandi ML, et al. Hypoparathyroidism in the adult: Epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment and challenges for future research. J Bone Min Res 2011;26:2317-2337.

  7. Khan M, Waguespack S, Hu M. Medical management of postsurgical hypoparathyroidism. Review article. Endocr Pract 2011;17(Suppl 1).

  8. De Sanctis V, Soliman A, Fiscina B. Hypoparathyroidism: from diagnosis to treatment. Curr Opin Endocrinol Diabetes Obes 2012;19:435-442.

  9. Mannstadt M, Clarke B, Vokes T, Brandi ML, et al. Efficacy and safety of recombinant human parathyroid hormone (1-84) in hypoparathyroidism (REPLACE): a double-blind, placebo-controlled, randomised, phase 3 study. Lancet Diabetes Endocrinol 2013;1:275-283.

  10. Kim SJ, Kim SY, Kim HB, Cho HC. Polyglandular autoimmune syndrome type III with primary hypoparathyroidism. Endocrinol Metab 2013;28:236-240.




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Med Int Mex. 2016;32