medigraphic.com
ISSN 1684-1824 (Electronic)

2016, Number 3

<< Back Next >>

Rev Méd Electrón 2016; 38 (3)

Urogenital micoplasmas as a cause of feminine infertility. Provincial Gynecoobstetric Hospital of Matanzas. 2014-2015

Arnold RM

Language: Spanish
References: 19
Page: 370-382
PDF size: 199.74 Kb.


ABSTRACT

Background: urogenital mycoplasmas (Mycoplasma hominis, Ureaplasma urealyticum) are among the most frequent bacterial species involved in the couple infertility, although they are part of the vagina regular flora.
Aims: determining the incidence of urogenital mycoplasmas in the samples of endocervical exudates of patients of the Provincial Consultation of Attention to Infertile Couple; classifying the severity of the detected infection and; identifying the isolated microorganisms’ sensibility-resistance to different antimicrobials.
Materials and methods: a cross-sectional, descriptive, observational study was carried out in the Provincial Teaching Gyneco-obstetric Hospital “Dr. Julio Rafael Alfonso Medina” of Matanzas in the period from November 2014 to January 2015. The universe was formed by the 117 female patients who fulfilled the criteria of inclusion and exclusion.
Outcomes: 56.4 % of the analyzed samples were positive, being Ureaplasma urealyticum the most frequent specie. Light infections predominated, in 59.09 %. The most referred symptom was leucorrhea with 42.73 %. Ureaplasma urealyticum showed higher resistance toward ofloxacin, with 82 %. There was not resistance of Mycoplasma hominis toward the antimicrobials used in the research. The coinfections were more resistant to azythromycin (100 %), ofloxacin (90 %), and erythromycin (80 %).
Conclusions: Ureaplasma urealyticum was the most isolated microorganism. The most frequent symptom was leucorrhea. Light infections predominated. Ureaplasma urealyticum shows higher resistance to antimicrobials than Micoplasma hominis. Both are highly sensible to pefloxacin and minocycline.


REFERENCES

  1. Ortiz Rodríguez EC, Hechavarría Calderín CE, Ley Nag M, et al. Estudio de Chlamydia trachomatis, Ureaplasma urealyticum y Mycoplasma hominis en pacientes infértiles y abortadoras habituales. Rev Cubana Obstet Ginecol [Internet]. 2010 [citado 13 Nov 2014];36(4):573-84. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-600X2010000400011

  2. Urdaneta J, Cantillo E, Alarcón A, et al. Infertilidad tubárica e infección genital por Chlamydia trachomatis-Ureaplasma urealyticum. Rev Chil Obstet Ginecol [Internet]. 2013 [citado 13 Nov 2014];78(1):32-43. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717- 75262013000100006&lng=es

  3. López Ávila KB, Zavala Castro J, Arias León JJ, et al. Infertilidad humana causada por Mycoplasma spp. Rev Biomed [Internet]. 2014 [citado 13 Nov 2014];25:74-90. Disponible en: http://www.medigraphic.com/pdfs/revbio/bio- 2014/bio142e.pdf

  4. Llop Hernández A, Valdés Dapena Ma, Zuaso Silva J. Microbiología y parasitología médica. Tomo I. Cap 38 [ìnternet]. La Habana: ECIMED; 2009 [citado 13 Nov 2014 ]. 419-26 p. Disponible en: http://www.bvs.sld.cu/libros_texto/morfofisiologia/indice_p.htm

  5. Murray P, Rosenthal KS, Pfaüer MA. Microbiología Médica. Cap 44. 5ta ed. España, S: Elsevier. A; 2007. 443-7 p.

  6. Vázquez F, Antonio Lepe J, Otero L, et al. Diagnóstico microbiológico de las infecciones de transmisión sexual. Enferm infecc microbiol clín [Internet]. 2008 [citado 13 Nov 2014];26(1):32-7. Disponible en: http://linkinghub.elsevier.com/retrieve/pii/S0213005X08726491?via=sd

  7. Fernández Molina C, Zamora Martínez Y, Rodríguez Preval N, et al. Diagnóstico de Mycoplasma hominis, Ureaplasma parvum y Ureaplasma urealyticum en pacientes con vaginosis bacteriana. Rev Cubana Med Trop [Internet]. 2007 Ago [citado 29 Ene 2015 ];59(2): Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0375- 07602007000200006&lng=es

  8. Pandelidis K, McCarthy A, Kirsty L, et al. Role of Biofilm Formation in Ureaplasma Antibiotic Susceptibility and Development of Bronchopulmonary Dysplasia in Preterm Neonates. Pediatr Infect Dis J [Internet].2013 April [citado 3 Ene 2015];32(4):394–8. Citado en PubMed; PMID: 23114371.

  9. Taylor-Robinson D, Jensen JS, Svenstrup H,et al. Difficulties experienced in defining the microbial cause of pelvic inflammatory disease. Int J STD AIDS. 2012 Jan;23(1):18–24. Citado en PubMed; PMID: 22362682.

  10. Manhart LE. Mycoplasma genitalium: ¿An emergent sexually transmitted disease? Infect Dis Clin North Am. 2013;27(4):779–92.Citado en PubMed; PMID:24275270.

  11. Ortega Figueroa LM, Álvarez Pineda AB, Águila Nogueira Y, et al. Detección de infección por Mycoplasma en las gestantes con riesgo de parto pretérmino. Rev Cubana Ginecol Obstet [Internet]. 2012 [citado 29 Ene 2015];38(2):161–9. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138- 600X2012000200003

  12. Rodríguez Pendás BV, Ortiz Rodríguez C, Santana Pérez F, et al. Micoplasma hominis, Ureaplasma urealyticum y bacterias aeróbicas en el semen de hombres que consultan por infertilidad. Rev Cubana Endocrinol [Internet]. 2013 Abr [citado 13 Nov 2014];24(1):47-56. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561- 29532013000100005&lng=es

  13. Díaz García FJ, Flores Medina S. Relación entre infertilidad masculina e infección genitourinaria por micoplasmas: Una actualización. Perinatol Reprod Hum [Internet]. 2013 Mar [citado 29 Ene 2015];27(1):21-34. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0187- 53372013000100004&lng=es

  14. Duque de Estrada Serrano MM. Aislamiento e identificación de Ureaplasma spp y Mycoplasma hominis en muestras endocervicales de pacientes infértiles [Tesis]. La Habana: Instituto Superior Ciencias Médicas. Facultad Comandante Manuel Fajardo; 2008.

  15. Díaz Rigau L, Cabrera LE. Frecuencia y susceptibilidad antimicrobiana de Ureaplasma urealyticum y Mycoplasma hominis en pacientes con síndrome de flujo vaginal. La Habana: 8vo Congreso de Microbiología; 2014.

  16. Sanchén Casas A, Rodríguez Fernández OM, Torres Frómeta LD, et al. Hallazgos de Micoplasma hominis y Ureaplasma urealyticum en mujeres con infecciones urogenitales. AMC [Internet]. 2013 [citado 29 Ene 2015];17(3):309-21. Disponible en: http://www.medigraphic.com/pdfs/medicocamaguey/amc-2013/amc133g.pdf

  17. Solís Martínez R, Vázquez Castillo T, Celis S, Hernández Callejas L. Susceptibilidad de Mycoplasma hominis y Ureaplasma urealyticum ante diferentes antibióticos. Rev Med Univ Veracruz [Internet]. 2006 Dic [citado 29 Ene 2015];6(2):11-5. Disponible en: http://www.medigraphic.com/pdfs/veracruzana/muv-2006/muv062c.pdf

  18. Krausse R, Schubert S. In-vitro activities of tetracyclines, macrolides,fluoroquinolones and clindamycin against Mycoplasma hominis and Ureaplasma ssp. isolated in Germany over 20 years. Clin Microbiol Infect. 2010;16(11):1649-55. Citado en Pubmed; PMID: 20047607.

  19. Yasuhiro K, Yukiko N, Tetsu W, et al . In Vitro Activity of Five Quinolones and Analysis of the Quinolone Resistance-Determining Regions of gyrA, gyrB, parC, and parE in Ureaplasma parvum and Ureaplasma urealyticum Clinical Isolates from Perinatal Patients in Japan. Antimicrobial Agents and Chemotherapy. 2015 April;59(4):34-9. Citado en PubMed; PMID: 25645833.




2020     |     www.medigraphic.com