Piero Portincasa IG

Language: English
References: 6
Page: 300-302
PDF size: 129.38 Kb.

Text Extraction

Chronic hepatitis C virus infection (CHC) is currently the leading cause of liver cirrhosis, hepatocellular carcinoma and represents an of indication for liver transplantation. CHC therefore represents a major burden of care worldwide. Due to elevated costs of new antiviral agents, a careful stadiation of liver injury is required in the treatment decision making process, which is still mainly based on liver histology from biopsy specimens during an invasive procedure which carries some risks and sampling errors and is not well accepted by patients.

REFERENCES

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2. Shaheen AA, Myer RP. Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis C-related fibrosis: a systemic review. Hepatology 2007; 46: 912-21.

3. Brunt EM, Wong VWS, Nobili V, Day CP, Sookoian S, Maher JJ, Bugianesi E, et al. Nonalcoholic fatty liver disease. Nature Reviews Disease Primers 2015: 15080.

4. Krawczyk M, Portincasa P, Lammert F. PNPLA3-associated steatohepatitis: toward a gene-based classification of fatty liver disease. Semin Liver Dis 2013; 33:369-79. Doi: 10.1055/s-0033-1358525.

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