Ruiz-Bedolla E, López-Martínez B, Parra-Ortega I

Language: Spanish
References: 19
Page: 87-90
PDF size: 209.60 Kb.

ABSTRACT

Objective: This study aims to know the levels of L-canavanine in the serum of patients with systemic lupus erythematosus. Material and methods: We determined the levels of serum L-canavanine in 100 patients with systemic lupus erythematosus (SLE) and 100 samples of healthy subjects. Results: The levels of serum L-canavanine in healthy subjects were 1.8 to 3.8 mg/dL, with a mean of 3.1 mg/dL, and 3.8 to 16 mg/dL, with a mean of 7.1 mg/dL, in patients with systemic lupus erythematosus (p ‹ 0.01). The test was found to have a sensitivity of 96% and specificity of 95%. This is the first report evaluating serum canavanine in patients with SLE; therefore, it is not possible to compare results with other studies. Conclusions: These data suggest that measurement of serum L-canavanine may be useful in the diagnosis of systemic lupus erythematosus.

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