2016, Number S3
<< Back Next >>
Rev Mex Cardiol 2016; 27 (S3)
Factors of surgical morbidity and mortality in patients with chronic renal dysfunction undergoing coronary revascularization
Acuña-Tapia H, Galván-García JE
Language: Spanish
References: 28
Page: 110-120
PDF size: 224.54 Kb.
ABSTRACT
Introduction: In chronic kidney disease, cardiovascular diseases are responsible for 50% of mortality. In patients with cardiovascular diseases and chronic kidney disease, coronary artery bypass grafting is associated with better survival rates. The aim of this study was to identify the main factors of surgical morbidity and mortality in chronic kidney disease patients undergoing coronary artery bypass grafting, in a Mexican community.
Methods: The study design was descriptive and retrospective, all patients were included from March 2013 to February 2014. The information was obtained by consulting medical records and the information was analyzed with the statistical program SPSS v20.
Results: We analyzed 352 patients, of whom 43 patients were included in the study. A prevalence of 12.21% of chronic kidney disease was found, with an average of glomerular filtration rate of 50.43 ± 6.7 mL/min/1.73 m
2. Mortality was 9.3%, need of dialysis 9.3%, the incidence of postoperative myocardial infarction 4.7%, infectious complications 13.9 % and cardiac arrhythmias 20.9%. The average hospital stay was 24.6 ± 10.53 days.
Conclusion: With regard to literature a lower prevalence of chronic kidney disease among coronary artery bypass graftin was found, with similarly mortality, and increased postoperative morbidity.
REFERENCES
Wright RS, Reeder GS, Herzog CA et al. Acute myocardial infarction and renal dysfunction: a high-risk combination. Ann Intern Med. 2002; 137 (7): 563-570.
National Kidney Fundation. Definition and classification of stages of chronic kidney disease. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification, and Stratification. Am J Kidney Dis. 2002; 39 (Suppl 1): S1-S266. Available in: www.kidney.org/professionals/kdoqui/guidelines_ckd/toc.htm
Froissart M, Rossert J, Jacquot C. Predictive performance of the modificacion of diet in renal disease and cockcroft-gault equations for estimating renal function. J Am Soc Nephrol. 2005; 16 (3): 763-773.
Brosius III FC et al. Detection of chronic kidney disease in patients with or at increased risk of cardiovascular disease. Circulation. 2006; 114: 1083-1087.
Cozzolino M, Brancaccio D, Gallieni M, Slatopolsky E. Pathogenesis of vascular calcification in chronic kidney disease. Kidney Int. 2005; 68 (2): 429-436.
Goodman WG, Goldin J, Kuizon BD et al. Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Engl J Med. 2000; 342 (20): 1478-1483.
Russo D, Corrao S, Miranda I et al. Progression of coronary artery calcification in predialysis patients. Am J Nephrol. 2007; 27 (2): 152-158.
Shroff RC, Shanahan CM. The vascular biology of calcification. Semin Dial. 2007; 20 (2): 103-109.
Moe SM, Chen NX. Mechanisms of vascular calcification in chronic kidney disease. J Am Soc Nephrol. 2008; 19 (2): 213-216.
Pannier B, Guérin AP, Marchais SJ, Safar ME, London GM. Stiffness of capacitive and conduit arteries: prognostic significance for end-stage renal disease patients. Hypertension. 2005; 45 (4): 592-596.
Reddan DN, Szczech LA, Tuttle RH, Shaw LK, Jones RH, Schwab SJ et al. Chronic kidney disease, mortality, and treatment strategies among patients with clinically significant coronary artery disease. J Am Soc Nephrol. 2003; 14: 2373-2380.
American Association for Thoracic Surgery, Society of Cardiovascular Anesthesiologists, and Society of Thoracic Surgeons. Guideline for Coronary Artery Bypass Graft Surgery. Circulation. 2011; 124: 652-735.
Hemmelgarn BR, Southern D. Survival after coronary revascularization among patients with kidney disease. Circulation. 2004; 110 (14): 1890-1895.
Holzmann MJ, Sartipy U. Relation between preoperative renal dysfunction and cardiovascular events (stroke, myocardial infarction, or heart failure or death) within three months of isolated coronary artery bypass grafting. Am J Cardiol. 2013; 112 (9): 1342-1346.
Holzmann MJ, Ahlbeack E, Jeppsson A, Sartipy U. Renal dysfunction and longterm risk of ischemic and hemorrhagic stroke following coronary artery bypass grafting. Int J Cardiol. 2013; 168: 1137-1142.
Cooper WA, O’Brien SM. Impact of renal dysfunction on outcomes of coronary artery bypass surgery, results from the society of thoracic surgeons national adult cardiac database. Circulation. 2006; 113 (8): 1063-1070.
James MT, Ghali WA, Knudtson ML, Ravani P, Tonelli M, Faris P et al. Associations between acute kidney injury and cardiovascular and renal outcomes after coronary angiography. Circulation. 2011; 123 (4): 409-416.
Holzmann MJ, Gardell C, Jeppsson A, Sartipy U. Renal dysfunction and long term risk of heart failure after coronary artery bypass grafting. Am Heart J. 2013; 166 (1): 142-149.
Olsson D, Sartipy U, Braunschweig F, Holzmann MJ. Acute kidney injury following coronary artery bypass surgery and long-term risk of heart failure. Circ Heart Fail. 2013; 6 (1): 83-90.
Anavekar NS, McMurray JJ, Velazquez EJ, Solomon SD, Kober L, Rouleau JL et al. Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction. N Engl J Med. 2004; 351 (13): 1285-1295.
Anderson RJ, O’Brien M, MaWhinney S, VillaNueva CB, Moritz TE, Sethi GK et al. Renal failure predisposes patients to adverse outcome after coronary artery bypass surgery: VA Cooperative Study #5. Kidney Int. 1999; 55 (3): 1057-1062.
Szczech LA, Reddan DN. Differential survival after coronary revascularization procedures among patients with renal insufficiency. Kidney Int. 2001; 60 (1): 292-299.
Holzmann MJ, Ahnve S, Hammar N, Jorgensen L, Klerdal K, Pehrsson K et al. Creatinine clearance and risk of early mortality in patients undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2005; 130 (3): 746-752.
Holzmann MJ, Jernberg T. Long-term cardiovascular outcomes in patients with chronic kidney disease undergoing coronary artery bypass graft surgery for acute coronary syndromes. J Am Heart Assoc. 2014; 3: e000707.
Brown JR, Cochran RP. Long-term survival after cardiac surgery is predicted by estimated glomerular filtration rate. Ann Thorac Surg. 2008; 86 (1): 4-11.
Zakeri R, Freemantle N, Barnett V. Relation between mild renal dysfunction and outcomes after coronary artery bypass grafting. Circulation. 2005; 112 (9 Suppl.): I-270-I-275.
Levey AS, Beto JA, Coronado BE, Eknoyan G. Controlling the epidemic of cardiovascular disease in chronic renal disease: what do we know? What do we need to learn? Where do we go from here? National Kidney Foundation Task Force on Cardiovascular Disease. Am J Kidney Dis. 1998; 32 (5): 853-906.
Serruys PW, Morice MC, Kappetein AP. Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease (SYNTAX). N Engl J Med. 2009; 360 (10): 961-972.