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2016, Number 2

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Dermatología Cosmética, Médica y Quirúrgica 2016; 14 (2)

Basal cell carcinoma. Treatment with intralesional alfa 2b interferon

Vega GLG
Full text How to cite this article

Language: Spanish
References: 26
Page: 102-107
PDF size: 292.86 Kb.


Key words:

basal cell carcinoma, immunotherapy, interferon alfa 2b (INFα2b).

ABSTRACT

Background: basal cell carcinoma is the most common cancer and surgery is the treatment of choice. There are nonsurgical options, such as intralesional alfa 2b interferon.
Objetive: the aim was to establish the safety and efficacy of iINFα2b and report if the topography and morphology of the lesion influence in the clinical response.
Methods: we studied 78 patients at Dermatology section in a Hospital Vasco de Quiroga, issste, in the city of Morelia, Michoacán. All patients included with either primary or recurrent tumor, and treated with 2 million of iu of INFα2b intralesional three times a week, with a total dosis of 18 000 000 ui.
Results: the global positive response was 84.6%, and the clinical types, nodular and morpheaform, had a better response and good aesthetic results.
Conclusions: infα2b is a safe and efficacious alternative treatment of basal cell carcinoma, especially the nodular and morpheaform types.


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Dermatología Cosmética, Médica y Quirúrgica. 2016;14