2016, Number 2
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Dermatología Cosmética, Médica y Quirúrgica 2016; 14 (2)
Lymphoma t/nk extranodal, nasal type: a case report in adolescent
Ballinas-Aquino J, Arenas R, Vega-Memije ME, Toussaint-Caire S
Language: Spanish
References: 17
Page: 131-136
PDF size: 346.99 Kb.
ABSTRACT
Lymphoma t/nk nasal type is predominantly an extranodal lymphoma,
associated with Epstein-Barr virus. Usually involving the
nose and the upper respiratory and digestive tract. It is characterized
by vascular damage with angiocentric and angiodestructive
patterns, with lymphocytes of different sizes, mixed
with eosinophils, plasma cells and histiocytes. It may appear an
inflammatory infiltrate extending to the subcutaneous tissue,
leading to necrosis and large nasal ulcerations. It mainly affects
adults aged 50 to 60 years, preferably males (2: 1). Worldwide
there are few reported cases in adolescents.
A 15 year-old male, with a six months history of a facial
ulceration affecting right nasal wing, cheek and upper portion
of the lip. The ulceration was a 5 cm in diameter with a depth
of 1.5 cm, covered by seropurulent exudate and necrotic areas
with erythematous border and crusts. Immunohistochemistry
confirmed t/nk lymphoma, extranodal nasal type. He received
chemotherapy and radiation therapy and patient survival after
diagnosis was 15 months.
REFERENCES
Aozasa, K. y Zaki, M., “Epidemiology and pathogenesis of nasal nk/tcell lymphoma: a mini-review”, 2011, 11, http://www.hindawi.com/ journals/tswj/2011/218136/abs/.
Wing-yan, A., Dennis, W., Tanin, I., Shigeo, N., Won-Seog, K., Ivy, S., Julie, V., James, A., Raymond, L., “Clinical differences between nasal and extranasal natural killer/t-cell lymphoma: a study of 136 cases from the International Peripheral t-Cell Lymphoma Proyect”, Blood Journal, 2009, 17: 3931-3937.
Fernández-Flores, A., “Epstein-Barr virus in cutaneous pathology”, Am J Dermatopathol, 2013, 8: 763-783.
Li, S., Feng, X., Li, T., Zhuang, S., Zuo, Z., Lin, P., Konoplev, S., Bueso- Ramos, C., Vega, F., Medeiros, J. y Yin, C., “Extranodal nk/t-cell lymphoma, nasal type”, Am J Surg Pathol, 2013, 1: 14-23.
“Linfoma nasal angiocéntrico natural killer. Una entidad clinicopatológica distinta”, 2004, 5, http://dialnet.unirioja.es/servlet/articulo? codigo=4954505.
Moreno, M., Pierzchalski, J., Ivanov, M., Verea, M. y Torchiari, F., “Linfoma extraganglionar de células t/nk: presentación de un caso clínico y revisión de la literatura”, Arch Argent Dermatol, 2014, 64: 57-60.
Lara, A., Morales, M., García, M. y Ball de Picón, E., “Linfoma cutáneo de células t/nk extraganglionar tipo nasal. Reporte de un caso y revisión de la literatura”, Dermatol Venez, 2010, 1: 39-43.
“Linfoma no Hodgkin oncoguía”, 2011, 3, http://www.incan.org.mx/ revistaincan/elementos/documentosPortada/1327326441.pdf.
Torre, A., Llorente, S., De Vicente, J., Junquera, L. y López-Arranz, J., “Linfoma nasal de células t/nk”, Rev Esp Cir Oral y Maxilofac, 2005, 2: 100-108.
“Diagnóstico serológico de la infección por el virus Epstein-Barr”, 1999, https://www.seimc.org/contenidos/ccs/revisionestematicas/ serologia/ebvrev.pdf.
Vilcahuamán, V., Moisés, C., Sánchez, G. y Carbajal, D., “Linfoma t/nk fenotipo t citotóxico”, Folia Dermatol Peru, 2009, 3: 141-147.
Romero, M., Lazos, M., Cruz, H., Vázquez, P., Cruz, A., Velásquez, G., Rivas, S. y Feller, A., “Linfomas no Hodgkin de nariz, paladar y orofaringe en pacientes del Hospital General de México”, Rev Med Hosp Gen Mex, 2008, 3: 119-125.
Jang, K., Choi, H., Sung, K., Moon, K., Hoh, J., Kwon, Y. et al., “Primary cd56+ nasal-type t/natural killer-cell subcutaneous panniculitic lymphoma: presentation as haemophagocytic syndrome”, Be J Dermatol, 2001, 141: 706-709.
Ansai, S., Maeda, K., Yamakawa, S., Matsuda, M., Saitoh, S., Suwa, S. et al., “cd56-positive (nasal-type t/nk cell) lymphoma arising on the skin. Report of two cases and review of the literature”, J Cutan Pathol, 1997, 24: 468-476.
Miyamoto, T., Yoshino, T., Takehisa, T., Hagari, Y. y Mihara, M., “Cutaneous presentatios of nasal/nasal type t/nk cell lymphoma: clinicopathological findings of four cases”, Br J Dermatol, 1998, 139: 481-487.
Savoia, P., Fierro, M., Novelli, M., Quaglino, P., Verrone, A., Geuna, M. et al., “cd56-positivo linfoma cutáneo: una entidad mal reconocida en el espectro de la enfermedad cutánea primaria”, Br J Dermatol, 1997, 137: 966-971.
Rodríguez-Pinilla, S., Barrionuevo, C., García, J., Martínez, M., Pajares, R., Montes-Moreno, S. et al., “ebv-associated cutaneous t/nk-cell lymphoma. Review of a series of 14 cases from Peru in children and young adults”, Am J Surg Pathol, 2010, 12: 1773-1782.
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