Morones-Esquivel I, Salgado-Muñoz TG, Gonzaga-López TI, Matamoros-Mejía AP, Terán-González JO, Arteaga-Vázquez S, Castro-D’Franchis LJ, Reyes-Jiménez AE, López-González DS, Meza-Oviedo D

Language: Spanish
References: 13
Page: 381-387
PDF size: 611.99 Kb.

ABSTRACT

Background: Increasing antimicrobial resistance is now a major threat to public health. Enterobacteriaceae with extended-spectrum beta-lactamase (ESBL) are recognized as a major cause of nosocomial and community acquired infections. Its development is related to the misuse of antibiotics, mainly third generation cephalosporins.
Objetive: To analyze the development of ESBL enterobacteria, during the years 2012, 2013 and 2014 in blood and urine isolates to determine if there is a statistically significant increase.
Material and Method: An observational, cross-sectional, retrospective and analytical study was done. Categorical variables were compared using χ² test with Yates continuity correction.
Results: 1,019 isolates were reported: Blood isolates: In 2012: 49% ESBL and 51% not ESBL. In 2013: 71% ESBL and 29% not ESBL. In 2014: 59% ESBL and 41% not ESBL. Urine isolates: In 2012: 28% ESBL and 72% not ESBL. In 2013: 27% ESBL and 73% not ESBL. In 2014: 33% ESBL and 67% not ESBL. Blood isolates were obtained for p=0.1273 and urine isolates p= 0.2366.
Conclusions: There was no statistically significant increase. It was shown a high development of ESBL. The prevalence of ESBL is important because it confers resistance to multiple antibiotic including ceftriaxone, one of the antibiotics mostly used, also helps to generate strategies for their control.

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