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ISSN 1028-4796 (Print)

2016, Number 2

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Rev Cubana Plant Med 2016; 21 (2)

Ichtyotoxic activity of two colombian species extracts fromthe genus Meriania Swartz (melastomataceae)

Aguirre NM, Aguirre SM, Isaza MJH, Colmenares DAJ, Ocampo SDM, Jaramillo SMT, Galvis GJH

Language: Spanish
References: 16
Page: 203-214
PDF size: 286.41 Kb.


ABSTRACT

Introduction: Melastomataceae is the seventh largest family in the plant kingdom and has been widely used in traditional medicine for the treatment of some diseases. In Colombia it is represented by around 62 genera, of which Meriania has been understudied, without presenting reports in the literature of its chemical and biological properties; so the study of their ichtyotoxic properties constitutes an approach in the search for active substances that advance knowledge of genus and in finding promising compounds with biological applications.
Objetive: To evaluate the ichtyotoxic activity of extracts of different polarity of Meriania speciosa (Bonpl.) and Merianiaquintuplinervis Naudin.
Methods: The extracts of different polarity (n-hexane, acetone 70 %, methanol, ethyl acetate, n-butanol and water) of both species were evaluated against guppy (Poeciliareticulata Peters), subjected for 24 h to action extracts for quantification of the percentage of ichtyotoxic activity in a semiquantitative scale and the observation Finn Sandberg-Irwintest and histopathological sections were obtained, in order to identify potential injuries from plant extracts.
Results: According to ichtyotoxic activity rates obtained in this study, the evaluated substances are classified as inactive; however, the test results indicate that the substances affect the nervous system and produce liver damage in fishes.
Conclusions: The plant extracts of the Merianiaspecies studied have different behaviors, as M. speciosahas a psychoactive effect on fishes, mainly altering the central nervous system, while M. quintuplinervisis more related to a moderate level of toxicity as well as causing a vasodilator effect found in the liver of P. reticulata.


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