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Colegio de Medicos y Cirujanos República de Costa Rica
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2016, Number 619

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Rev Med Cos Cen 2016; 73 (619)

Ejercicio como tratamiento anti-inflamatorio

Abarca A
Full text How to cite this article

Language: Spanish
References: 11
Page: 279-284
PDF size: 180.60 Kb.


Key words:

persistent systemic inflammation, myokines.

ABSTRACT

During the past two decades, advances in research have revealed the role of exercise as a therapy for inflammatory diseases. One of the most important of these advances is the discovery that skeletal muscle communicates with other organs and tissues by secreting proteins called myokines. Some myokines, by different mechanisns, induce anti-inflammatory responses with each bout of exercise and mediate long-term exerciseinduced improvements in cardiovascular risk factors, having an indirect antiinflammatory effect. Therefore, contrary to fears that physical activity might aggravate inflammatory pathways, exercise is now believed to be a potential treatment for patients with inflammatory diseases.


REFERENCES

  1. Benatti, F., & Pedersen, B. (2015). Exercise as an anti-inflammatory therapy for rheumatic diseases— myokine regulation. Nature Reviews-Rheumatology, 86-97.

  2. Buresh, R., & Berg, K. (2014). Role of Exercise on Inflammation and Chronic Disease. Strenght and Conditioning Journal, 87-93.

  3. Catoire, M., & Kersten, S. (2015). The search for exercise factors in humans. FASEB Journal, 1-14.

  4. Horsburgh, S., Robson-Ansley, P., Adams, R., & Smith, C. (2015). Exercise and Inflammation-related Epigenetic Modifications: Focus on DNA Methylation. Exercise Immunology Review, 26-41.

  5. Kohut, M., McCann, D., Russell, D., Kanopka, D., Cunnick, J., Franke, W., y otros. (2006). Aerobic exercise, but not flexibility/resistance exercise, reduces serum IL-18, CRP, and IL-6 independent of beta-betablockers, BMI, and psychosocial factors. Brain, Behavior and Immunity, 201- 209.

  6. Kumar, V., Abbas, A., Fausto, N., & Aster, J. (2010). Robins and Cotran: Pathologic Basis of Disease. Philadelphia: Saunders Elsevier.

  7. Lavie, C., Arena, R., Swift, D., Johannsen, N., Sui, X., Earnest, C., y otros. (2015). Exercise and the Cardiovascular System. Circulation Research, 207-219.

  8. Mathur, N., & Pedersen, B. (2008). Exercise as aMean to Control Low- Grade Systemic Inflammation. Mediators of Inflammation , 1-6.

  9. 9- Nicklas, B., & Brinkley, T. (2009). Exercise Training as a Treatment for Chronic Inflammation in the Elderly. Exercise and Sport Sciences Reviews, 165-170.

  10. Perdersen, B., & Saltin, B. (2006). Evidence for prescribing exercise as therapy in chronic disease . Scandinavian Journal of Medicine & Science in Sports, 3-63.

  11. Starkie, R., Ostrowski, S., Jauffred, S., Febbraio, M., & Pedersen, B. (2003). Exercise and IL-6 infusion inhibit endotoxin-induced TNFalpha production in humans 17. FASEB, 884-886.




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Rev Med Cos Cen. 2016;73