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Revista Cubana de Oftalmología

ISSN 1561-3070 (Electronic)
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2016, Number 2

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Rev Cub Oftal 2016; 29 (2)

Mitomycin C-associated needle revision in encapsulated filtering blebs

Fumero GFY, Cárdenas CD, Fernández AL, Piloto DI, Vidal CM, Obret MI, Díaz ÁY
Full text How to cite this article

Language: Spanish
References: 18
Page: 189-198
PDF size: 114.35 Kb.


Key words:

needle revision, cystitomy, mitomicyn-C, encapsulated blebs, failed trabeculectomy, antimetabolites.

ABSTRACT

Objective: to determine the medium-term effectiveness of subconjuntival mitomicyn- C associated to needle revision on encapsulated filtering bleb after trabeculectomy.
Methods: prospective, descriptive and observational case series study (30 eyes, 30 patients) with a history of Tenon cyst after short term trabeculectomy (1 month -1year). These patients underwent needle revision associated to subconjuntival 0,01 % mitomycin injection to completing three doses in every other day. The intraocular pressure and the use of hypotensive drops preoperatively and postoperatively were evaluated seven days, one month, three months, one year and two years after the procedure. The success of intervention was defined as total when the intraocular pressure was less than 21 mmHg without hypotensive drops and partial with hypotensive drops. Surgical complications were recorded.
Results: the mean preoperative intraocular pressure decreased significantly from 27,06 ± 5,2 mmHg to 13,10 ± 3,3 mmHg, 14,83 ± 3,68 mmHg and 16,70 ± 3,38 mmHg one week, one month and three months after surgery and remained stable (16,70 ± 2,18 mmHg) for 2 years, p ‹ 0,001 for each preoperative and postoperative comparison; this represented an intraocular pressure reduction of 51,8 %; 44,4 % and 37 % after one week, one month, and up to 2 years, respectively. The mean number of hypotensive drops lowered significantly from 2,0 ± 0,0 (preoperative) to 0,4 ± 0,0 (two years after surgery), being p ‹ 0,001. Total success was attained in 70 % of cases and partial in 30 % after 2 years. Surgical complications were subconjuntival haemorrhage (in all patients), atalamy (40 %) and positive Seidel index (26,7 %).
Conclusion: subconjuntival mitomicyn-C injection-associated needle revision for encapsulated bleb reduces intraocular pressure by 37 % during the first 2 years after the procedure with minimal complications.


REFERENCES

  1. Fernández L, Padilla CM, Obret I, Piloto I, Fumero FY. Factores pronósticos del fallo de la trabeculectomía en una población cubana. Arch Soc Esp Oft. 2015 [citado 26 enero de 2016];90(12). Disponible en: http://dx.doi.org/10.1016/j.oftale.2015.12.005

  2. Zarei R, Shahhosseini S, Faragee-Oskoueel G. Needle revision with Mitomycin-C in encapsulated Blebs. Acta Med Iran. 2008;46(4):295-8.

  3. Ruderman JM. Revising the failing filtration bleb. Techn Ophthalmol. 2005;3:133-7.

  4. Eid TM, Spaeth GL. The glaucoma. Philadelphia: Lippincott, Williams & Wilkins; 2000.

  5. ;Kahook MY. Needle bleb revision with bevacizumab. Techniques in Ophthalmology. 2008 [citado 7 de mayo de 2015];6(4):111-3. Disponible en: http://journals.lww.com/technique

  6. Kanski JJ. Clinical Ophthalmology, a systematic approach. Elsevier; 2012

  7. Sharmila R, Prashanth R, Krishnadas R. Needle revision of failing filtering blebs may spare patients and physicians another trip to the OR. AIOC proceeding: Glaucoma session II. 2008 [citado 5 de abril de 2015]. p. 271-3. Disponible en: http://www.aios.org/proceed08/papers/GLU-II/Glu-II8.pdf

  8. Perucho S, Gutiérrez E, Montero M, Mencía E, Lago MD. Repermeabilización mediante revisión con aguja de ampollas de filtración con fracaso tardío tras cirugía de glaucoma. Arch Soc Esp Oftalmol. 2006 [citado 5 de abril de 2015];81(9). Disponible en: http://scielo.isciii.es/scielo.php?pid=S036566912006000900006&script=sci_arttext

  9. Elsayed TH, El-Raggal TM. Mitomycin-C needle bleb revision in congenital glaucoma. Afr J Ophthalmol. 2010;17(4):369-73.

  10. Arzuaga E, Fumero F, González S, Batista M. Revisión por aguja de la bula de filtración, una alternativa terapéutica en pacientes trabeculectomizados. Rev Cubana Oftalmol. 2012 [citado 26 de enero de 2016];25(Supl. 1). Disponible en http://www.revoftalmologia.sld.cu/index.php/oftalmologia/issue/view/7

  11. Maestrini HA, Fernandes TA, Matoso HD, Amaral WO, Maestrini AA. Scleral injury caused by needling revision with adjunctive mytomicin-C: case report. Arq Bras Oftalmol. 2011;74(2):134-5.

  12. Amini H, Esmaili A, Zarei R, Amini N, Daneshvar R. Office-based slit-lamp needle revision with adjunctive mitomycin-C for late failed or encapsulated filtering blebs. Middle East Afr J Ophthalmol. 2012;19(2):216-21.

  13. Maestrini HA, Cronemberger S, Matoso HD, Reis JR, Mérula RV, Filho AD, et al. Late needling of flat filtering blebs with adjunctive mitomycin-C: efficacy and safety for the corneal endothelium. Ophthalmology. 2011;118(4):755-62.

  14. Güerri N, Calvo P. Actualización del tratamiento de las ampollas encapsuladas postrabeculectomía. Arch Soc Esp Oftalmol. 2011;86(6):173-5.

  15. Suzuki R, Susanna R. Early transconjunctival needling revision with 5-fluorouracil versus medical treatment in encapsulated blebs: a 12-month prospective study. Sao Paulo: Clinics. 2013;68(10):1376-9.

  16. Dalvi R, Orzech N, Kranemann C, Birt CM. Five-year results of 5-fluorouracil augmented needling revision of failing blebs. Ophthalmic Surg Las Imag. 2012;43(1):32-8.

  17. Tatham A, Sarodia U, Karwatowski W. 5-Fluorouracil augmented needle revision of trabeculectomy: does the location of outflow resistance make a difference? J Glauc. 2013;22(6):463-7.

  18. Rashad MA. Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination. Clin Ophthalmol. 2013:7:15-22.




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Rev Cub Oftal. 2016;29