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Colegio de Medicos y Cirujanos República de Costa Rica

2016, Number 619

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Rev Med Cos Cen 2016; 73 (619)

Morfea: El desequilibrio entre la produccion y la destruccion del colágeno

Alfaro CK

Language: Spanish
References: 20
Page: 351-354
PDF size: 144.44 Kb.


ABSTRACT

Localized scleroderma is a connective tissue disorder generally involving the entire dermis and usually limited to the subcutaneous tissue; however, it may progress to large indurated plaques, growth retardation, muscle atrophy, and even to flexion deformities or poorly healing ulcers. The underlying pathogenesis of morphea is incompletely understood at this time, but the last investigations seem to involve an imbalance between collagen production and destruction.


REFERENCES

  1. Browning, J. (2013). Pediatric Morphea. Elsevier. Vol. 31. Pp. 229- 237.

  2. Das, S. et al. (2014). Correlates of self-reported quality of life in adults and children with morphed. J Am Acad Dermatol. Vol. 70. Nº5. Pp 904-910.

  3. Fett, N y Werth, V. (2011). Update on morphea. Part I. Epidemiology, clinical presentation, and pathogenesis. J Am Acad Dermatol. Vol. 64. Nº2. Pp 217-228.

  4. Fett, N. y Werth, V. (2011). Update on morphea. Part II. Outcome measures and tretment. J Am Acad Dermatol. Vol. 64. Nº2. Pp 231-242.

  5. Fernández, A. et al. (2011).Unilateral Generalized Morphea: A Case and Literature Review. Elsevier España. Vol. 7. Nº6. Pp 404-406.

  6. Gorkiewicz-Petkow Anna, Kalinska-Bienias Agnieszka, Systemic involvement in localized scleroderma / morphea, Clinics in Dermatology (2015), doi: 10.1016/j. clindermatol.2015.05.009.

  7. Grabell, D. et al.(2014). The role of skin trauma in the distribution of morphea lesions: A cross-sectional survey of the Morphea in Adults and Children cohort IV.J Am Acad Dermatol. Vol. 71. Nº3. Pp 493-498.

  8. Johnson, W. (2012). Morphea in adults and children cohort II: Patient with morphed experience delay in diagnosis and large variation in treatment. J Am Acad Dermatol. Vol 67, Nº 5. Pp 881-889.

  9. Nijhawan, R. (2011). Early localized morphea mimicking and acquired port-wine stain. J Am Acad Dermatol. Vol. 64. Nº4. Pp 779-782.

  10. Vasquez, R. et al. (2014). Recurrence of morphea after successful ultraviolet A1 phototherapy: A cohort study. J Am Acad Dermatol. Vol. 70. Nº 3. Pp 481-488.

  11. Browning, J. (2013). Pediatric Morphea. Elsevier. Vol. 31. Pp. 229- 237.

  12. Das, S. et al. (2014). Correlates of self-reported quality of life in adults and children with morphed. J Am Acad Dermatol. Vol. 70. Nº5. Pp 904-910.

  13. Fett, N y Werth, V. (2011). Update on morphea. Part I. Epidemiology, clinical presentation, and pathogenesis. J Am Acad Dermatol. Vol. 64. Nº2. Pp 217-228.

  14. Fett, N. y Werth, V. (2011). Update on morphea. Part II. Outcome measures and tretment. J Am Acad Dermatol. Vol. 64. Nº2. Pp 231-242.

  15. Fernández, A. et al. (2011).Unilateral Generalized Morphea: A Case and Literature Review. Elsevier España. Vol. 7. Nº6. Pp 404-406.

  16. Gorkiewicz-Petkow Anna, Kalinska-Bienias Agnieszka, Systemic involvement in localized scleroderma / morphea, Clinics in Dermatology (2015), doi: 10.1016/j. clindermatol.2015.05.009.

  17. Grabell, D. et al.(2014). The role of skin trauma in the distribution of morphea lesions: A cross-sectional survey of the Morphea in Adults and Children cohort IV.J Am Acad Dermatol. Vol. 71. Nº3. Pp 493-498.

  18. Johnson, W. (2012). Morphea in adults and children cohort II: Patient with morphed experience delay in diagnosis and large variation in treatment. J Am Acad Dermatol. Vol 67, Nº 5. Pp 881-889.

  19. Nijhawan, R. (2011). Early localized morphea mimicking and acquired port-wine stain. J Am Acad Dermatol. Vol. 64. Nº4. Pp 779-782.

  20. Vasquez, R. et al. (2014). Recurrence of morphea after successful ultraviolet A1 phototherapy: A cohort study. J Am Acad Dermatol. Vol. 70. Nº 3. Pp 481-488.




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