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Revista Cubana de Oftalmología

ISSN 1561-3070 (Electronic)
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2016, Number 2

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Rev Cub Oftal 2016; 29 (2)

Clinical and epidemiological behavior of patients suffering severe corneal ulcers

Pérez PZ, Arpasi HNL, Padilla GCM, Castillo PA, Guerra AM
Full text How to cite this article

Language: Spanish
References: 21
Page: 260-270
PDF size: 211.59 Kb.


Key words:

severe corneal ulcer, clinical and epidemiological behavior, severe keratitis, contact lenses.

ABSTRACT

Objective: to describe the clinical and epidemiological behavior of severe corneal ulcer in patients admitted to "Ramón Pando Ferrer" Cuban Institute of Ophthalmology from 2010 through 2014.
Methods: observational and cross-sectional study of 223 patients. The following variables were studied: age, sex, origin, occupation, eye and systemic diseases, previous surgery, non-surgical trauma, contact lens wear, previous steroids, duration, clinical form and isolated germ. For the statistical analysis, the study used percentages, means, nonparametric Fisher´s exact probability test, Pearson´s Chi Square, Mann Whitney´s U test.
Results: mean age was 46,3 ± 21,9. Patients aged 60 years or older (31,4 %), males (57,0 %), rural origin (57,8 %) predominated. Wearing contact lenses (22,4 %) was the most common predisposing factor. The median of days of progression on admission was 7 days. The most frequent clinical form of presentation was stromal ulcer (86,5 %) and perforated corneal ulcer (7,2 %). In 69,2 % of cultures, bacteria was obtained, being the Gram negative (Pseudomonas) predominant. The 33,3 % of cultures were filamentous fungi.
Conclusions: severe infectious keratitis was present in older adults, males and of rural origin. The most common predisposing factor was the contact lens wear. Gram negative bacteria were more frequently isolated.


REFERENCES

  1. Jeng BH, Gritz DC, Kumar AB, Holsclaw DS, Porco TC, Smith SD, et al. Epidemiology of Ulcerative Keratitis in Northern California. Arch Ophthalmol. 2010;128(8):1022-8.

  2. Basak SK, Basak S, Mohanta A, Bhowmick A. Epidemiological and microbiological diagnosis of suppurative keratitis in Gangetic West Bengal, eastern India. Indian J Ophthalmol. 2005;53(1):17-22.

  3. Karsten E, Watson SL, Foster LJ. Diversity of microbial species implicated in keratitis: a review. Open Ophthalmol J. 2012;6:110-24.

  4. Reddy JC, Murthy SI, Reddy AK, Garg P. Risk factors and clinical outcomes of bacterial and fungal scleritis at a tertiary eye care hospital. Middle East Afr J Ophthalmol. 2015;22(2):203-11.

  5. Keshav BR, Zacheria G, Ideculla T, Bhat V, Joseph M. Epidemiological characteristics of corneal ulcers in South Sharqiya Region. Oman Med J. 2008;23(1):34-9.

  6. Satpathi P, Satpathi S. Study of microbial keratitis in central India. J Infect Dev Ctries. 2012;6(3):295-8.

  7. Barrera B, Sánchez O, Marrero E, Díaz S. Queratoplastia en el Centro Oftalmológico del Hospital General Docente "Dr. Juan Bruno Zayas Alfonso". Rev Cubana Oftamol. 2011 [citado 26 de abril de 2016];15(12):1690-7. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029- 30192011001200002&lng=es

  8. Oladigbolu K, Rafindadi A, Abah E, Samaila E. Corneal ulcers in a tertiary hospital in Northern Nigeria. Ann Afr Med. 2013;12(3):165-70.

  9. Stapleton F, Carnt N. Contact lens-related microbial keratitis: how have epidemiology and genetics helped us with pathogenesis and prophylaxis. Eye. 2012;26(2):185-93.

  10. Abdelkader A. Cosmetic soft contact lens associated ulcerative keratitis in southern Saudi Arabia. Middle East Afr J Ophthalmol. 2014;21(3):232-5.

  11. Moid MA, Akhanda AH, Islam S, Halder SK, Islam R. Epidemiological Aspect and common Bacterial and Fungal isolates from Suppurative Corneal Ulcer in Mymensingh Region. Mymens Med J. 2015;24(2):251-6.

  12. Khater MM, Shehab NS, El-Badry AS. Comparison of Mycotic Keratitis with Nonmycotic Keratitis: An Epidemiological Study. J Ophthalmol. 2014 [citado 26 de abril de 2016]. Disponible en: http://dx.doi.org/10.1155/2014/254302

  13. Rahimi F, Hashemian MN, Khosravi A, Moradi G, Bamdad S. Bacterial keratitis in a tertiary eye centre in Iran: a retrospective study. Middle East Afr J Ophthalmol. 2015;22(2):238-44.

  14. Watanabe R, Ishii T, Yoshida M, Takada N, Yokokura S, Shirota Y, et al. Ulcerative keratitis in patients with rheumatoid arthritis in the modern biologic era: a series of eight cases and literature review. Int J Rheum Dis. 2015 [citado 26 de abril de 2016]. Disponible en: http://onlinelibrary.wiley.com/doi/10.1111/1756-185X.12688/full

  15. Knox Cartwright NE, Tole DM, Georgoudis P, Cook SD. Peripheral ulcerative keratitis and corneal melt: a 10-year single center review with historical comparison. Cornea. 2014;33(1):27-31.

  16. Schaefer F, Bruttin O, Zografos L, Guex-Crosier Y. Bacterial keratitis: a prospective clinical and microbiological study. Br J Ophthalmol. 2001;85(7):842-7.

  17. Amescua G, Miller D, Alfonso EC. What is causing the corneal ulcer? Management strategies for unresponsive corneal ulceration. Eye. 2012;26(2):228-36.

  18. Kunimoto D, Sharma S, Garg P, Gopinathan U, Miller D, Rao G. Corneal ulceration in the elderly in Hyderabad, south India. Br J Ophthalmol. 2000;84(1):54-9.

  19. Ng AL, To KK, Choi CC, Yuen LH, Yim SM, Chan KS, et al. Predisposing Factors, Microbial Characteristics, and Clinical Outcome of Microbial Keratitis in a Tertiary Centre in Hong Kong: A 10-Year Experience. J Ophthalmol. 2015 [citado 26 de abril de 2016]. Disponible en: http://www.hindawi.com/journals/joph/2015/769436/abs/

  20. Nath R, Baruah S, Saikia L, Devi B, Borthakur AK, Mahanta J. Mycotic corneal ulcers in upper Assam. Indian J Ophthalmol. 2011;59(5):367-71.

  21. Mellado F, Rojas T, Cumsille C. Queratitis fúngica: revisión actual sobre diagnóstico y tratamiento. Arq Bras Oftalmol. 2013;76(1):52-6.




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Rev Cub Oftal. 2016;29