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Colegio de Medicos y Cirujanos República de Costa Rica

2016, Number 620

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Rev Med Cos Cen 2016; 73 (620)

Dermatitis atópica

Rivero GJI

Language: Spanish
References: 14
Page: 711-716
PDF size: 161.33 Kb.


ABSTRACT

Atopic dermatitis (AD) is a common, chronic, recurrent skin disease, with a multifactorial and complex etiology, usually associated with other atopic disorders such as allergic rhinitis or asthma. There is a clear pattern of inheritance (with maternal predilection), which can reach up to 80% if both parents carry the disease or up to 50% if only one suffers from AD. The presence of asthma or allergic rhinitis in parents, appear to be minor factors in the onset of dermatitis in children, suggesting specific genes for AD. New investigations on the pathophysiology of the disease suggest the implication of abnormalities in the normal microbiota of the skin, new interleukins and structural skin proteins like filaggrin.


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