José-Ramírez H, Palomeque-López A, Cruz-López N, Jennings-Aguilar Y, Guzmán-Ortiz JD, Hernández-Cortez J, Cárdenas HN

Language: Spanish
References: 26
Page: 22-27
PDF size: 300.09 Kb.

ABSTRACT

Gallbladder cancer is the most common malignant tumor of the gastrointestinal tract. It is considered highly lethal. The percentage of patients diagnosed with cancer after a simple cholecystectomy is 0.5-1.5%. The differential diagnosis includes benign conditions such as inflammatory and infectious biliary processes, including hydrocholecyst, pyocholecyst, and cholangitis, as well as parasitic infections such as E. histolytica (Entamoeba histolytica). The most common clinical manifestation of amebiasis is acute colitis. Only 10% of the subjects infected develop symptoms. The complications classify as intestinal and extraintestinal. Among the intestinal complications are hemorrhage, toxic megacolon, appendicitis, severe ulcerations, intestinal perforations, and ameboma. A small subpopulation develops severe extraintestinal amebiasis. Extraintestinal manifestations include, apart from hepatic abscess, pulmonary, cardiac, cutaneous and NS affections, with an elevated mortality rate ranging from 4 to 14%. Hepatic abscess is the most common extraintestinal manifestation, and there are reports even of an amebic spleen abscess; the finding of an amoebian abscess in the gallbladder has only been reported twice previously, and even though it is considered extremely rare, it must be considered as a differential diagnosis of gallbladder cancer.

REFERENCES

1. Kanthan R, Senger JL, Ahmed S, Kanthan SC. Gallbladder cancer in the 21st century. J Oncol. 2015; 2015: 967472. doi: 10.1155/2015/967472. Epub 2015 Sep 1.

2. Padilla-Rosciano AE, Cruz-Rodríguez A, Serna-Thomé MG, Calderillo-Ruiz G, Vela-Sarmiento I, López- Basave HN, et al. Cáncer de vesícula y vías biliares.Manual de Oncología: procedimientos médico quirúrgicos. 5.a edición. McGraw Hill; 2013.

3. Sateriale A, Huston CD. A sequential model of host cell killing and phagocytosis by Entamoeba histolytica. J Parasitol Res. 2011; 2011: 926706. doi: 10.1155/2011/926706.

4. Entamoeba taxonomy. Bull World Health Organ. 1997; 75: 291-294

5. Gil-Manrique LF, Soler-Morejón C, Crespo-Acebal L, Villa-Valdés M, Alfonso-Alfonso L, Contreras-Roja IC. Absceso esplénico amebiano. Presentación de un caso. Revista Cubana de Cirugía. 2011; 50: 560-569.

6. Ximénez C. Epidemiology of amebiasis in Mexico: a molecular approach. Arch Med Res. 2006; 37: 263- 265.

7. Caballer-Salcedo A, Vivero-Rogel M, Salvatierra B, et al. Seroepidemiology of amebiasis in Mexico. Am J Trop Med Hyg. 1994; 50: 412-419.

8. Aguirre-García M, Gutiérrez-Kobeh L, López-Vancell R. Entamoeba histolytica: adhesins and lectins in thetrophozoite surface. Molecules. 2015; 20: 2802-2815.

9. Campos-Rodríguez R, Jarillo-Luna RA, Larsen BA, Rivera-Aguilar V, Ventura-Juárez J. Invasive amebiasis: a microcirculatory disorder? Med Hypotheses. 2009; 73: 687-697.

10. Roca-Goderich R. Enfermedad diarreica aguda. Amebiasis intestinal. En: Temas de medicina interna. Tomo III. 4.a ed. La Habana: Editorial Ciencias Médicas; 2002. p. 526-529.

11. Salles JM, Salles MJ, Moraes LA, Silva MC. Invasive amebiasis: an update on diagnosis and management. Expert Rev Anti Infect Ther. 2007; 5: 893-901.

12. Patricio C, Amaral P, Lourenço J. An uncommon case of hepatopulmonary amoebiasis. BMJ Case Rep. 2014; 2014. pii: bcr2014204129. doi: 10.1136/bcr-2014- 204129.

13. Kunst H, Mack D, Kon OM, Banerjee AK, Chiodini P, Grant A. Parasitic infections of the lung: a guide for the respiratory physician. Thorax. 2011; 66: 528-536. doi: 10.1136/thx.2009.132217.

14. Haque R, Huston CD, Hughes M, Houpt E, Petri WA Jr. Amebiasis. N Engl J Med. 2003; 348: 1565-1573.

15. Pérez-Tamayo R, Montfort I, García AO, Ramos E, Ostria CB. Pathogenesis of acute experimental liver amebiasis. Arch Med Res. 2006; 37: 203-209.

16. Fang D, Shu D. Entamoeba histolytica liver abscess. CMAJ. 2010; 182: 1758.

17. Lal C, Huggins JT, Sahn SA. Parasitic diseases of the pleura. Am J Med Sci. 2013; 345: 385-389. doi: 10.1097/MAJ.0b013e318266e984.

18. Maldonado-Barrera CA, Campos-Esparza MR, Muñoz-Fernández L, Victoria-Hernández JA, Campos-Rodríguez R, Talamás-Rohana P, et al. Clinical case of cerebral amebiasis caused by E. histolytica. Parasitol Res. 2012; 110: 1291-1296. doi: 10.1007/s00436- 011-2617-8. Epub 2011 Aug 26.

19. Abdel Razek AA, Watcharakorn A, Castillo M. Parasitic diseases of the central nervous system. Neuroimaging Clin N Am. 2011; 21: 815-841, viii. doi: 10.1016/j. nic.2011.07.005.

20. Magaña ML, Fernández-Díez J, Magaña M. Cutaneous amebiasis in pediatrics. Arch Dermatol. 2008; 144: 1369-1372. doi: 10.1001/archderm.144.10.1369.

21. Fernández-Díez J, Magaña M, Magaña ML. Cutaneous amebiasis: 50 years of experience. Cutis. 2012; 90: 310-314.

22. Abdolrasouli A, de Vries HJ, Hemmati Y, Roushan A, Hart J, Waugh MA. Sexually transmitted penile amoebiasis in Iran: a case series. Sex Transm Infect. 2012; 88: 585-588. doi: 10.1136/sextrans- 2012-050577. Epub 2012 Aug 28.

23. Fonseca Aizpuru EM, Nuño Mateo FJ, Menéndez Calderon MJ, Arias Miranda IM, Rodríguez Díaz B. Splenic abscess: revision of 7 cases. An Med Interna (Madrid). 2007; 24: 511-512.

24. Hashim M. Pathological lesions of the gall-bladder associated with ulcerations and bilharziasis of the intestine. A case of amoebic dysentery in which the morbid histology of the gallbladder has revealed E.histolytica in its wall is recorded and the literature on “amoebic cholecystitis” is reviewed. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1934; 27: 399-407.

25. Fernández FAH, Robles CS, Carratalá FB, Espejo JM, Moreno FP. Colecistitis aguda alitiásica amebiana. Revista Española de las Enfermedades del Aparato Digestivo. 1990; 78: 41-42

26. Antiamoebic drugs for treating amoebic colitis. Cochrane Database of Systematic Reviews. The Cochrane Library, Issue 2, Art. No. CD006085. Cochrane Database of Systematic Reviews, Issue 2, 2015.