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2016, Number 3

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Rev Cubana Pediatr 2016; 88 (3)

New diagnosis of neonatal cardiac dynamics based on the dynamic systems and the fractal geometry

Rodríguez J, Prieto S, Correa C, Flórez M, López R, Alarcón C, Soracipa Y, Jattin J, Silva S, Valdés C

Language: Spanish
References: 30
Page: 266-280
PDF size: 243.11 Kb.


ABSTRACT

Background: the theory of dynamic systems and fractal geometry has been useful to evaluate the cardiac dynamics in adults and neonates. From this perspective, there has been recently developed a new diagnostic method of the chaotic cardiac dynamics in neonates.
Objective: to confirm through a blind study the diagnostic capacity of this methodology to differentiate normal neonatal cardiac registrations from cardiac disease registrations.
Methods: fifty nine registrations were analyzed; 10 with normal diagnoses and 49 with different heart diseases. Conventional diagnoses were masked and the maximum and minimal heart rates were measured every hour as well as the number of beats per hour during 21 hours. For each dynamics, simulations of total heart rate sequences were developed and attractors were generated as well as their fractal dimension was estimated and their occupational spaces in the Box Counting's fractal space were quantified, thus determining the mathematical-physical diagnosis.
Results: the fractal dimensions did not allow differentiating normality from disease. In contrast, it was possible to differentiate, through the occupational spaces of the chaotic attractors found, the normal states from the acute diseases to reach 100 % sensitivity and specificity rates and a Kappa coefficient equal to 1.
Conclusions: the diagnostic capacity of the devised methodology was confirmed at the clinical setting in addition to existence of acausal self-organization of the neonatal cardiac dynamics that sets differences between normality and disease, with preventive clinical applicability.


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