2016, Number 3
Rev Mex Patol Clin Med Lab 2016; 63 (3)
Implementation of the Foldscope as a device for cervical cancer diagnosis: A verification and evaluation study
Moya-Salazar J, Bruno M, Rojas-Zumaran V, Bhamla S, Prakash M
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ABSTRACTObjective: To implement, monitor and evaluate the implementation of Foldscope in the screening of cervical cancer in conventional exfoliative cytology. Material and methods: An exploratory, quasi-experimental double-blind research was conducted in Prakash Lab, Department of Bioengineering at Stanford University during May 2016. We selected 10 slides of cervical cytology, four negative for intraepithelial lesion or malignancy (NLIM) and six with cervical uterine abnormalities. The cytological characteristics of the smears were evaluated with both Foldscope and optical microscopy with 10x and 40x magnification lenses. Microphotography, an image station tool and image projection were used. Statistical analysis was performed using IBM SPSS. Results: From the comparison of images between the optical microscope and Foldscope, the same cytological features were found in the cells of both NLIM and preneoplastic or neoplastic lesions (p ‹ 0.001). However, the Foldscope evidenced a clear lack of clarity around the focal point and constraints in focus, which made necessary, more often than not, the use of the image station and image projection. Conclusions: Foldscope is an extraordinary tool for the diagnosis of cervical cancer; despite its obvious limitations, it is able to receive improvements to be made a cost-effective device exclusively for cancer diagnosis.