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ISSN 1561-3062 (Electronic)
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2016, Number 2

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Revista Cubana de Obstetricia y Ginecología 2016; 42 (2)

Vulvar carcinoma and treatment (200-2013)

Sánchez GL, Rodríguez IJM
Full text How to cite this article

Language: Spanish
References: 7
Page: 179-188
PDF size: 268.19 Kb.


Key words:

vulvar carcinoma, survival, surgical management.

ABSTRACT

Introduction: in recent years it the number of vulvar carcinomas has increased, especially in patients younger than 50, associated with the increase of number of cases of vulvar intraepithelial neoplasia.
Objective: describe our casuistic of vulvar neoplasia in the last 14 years and Determine prognostic variables for survival.
Methods: aretrospective review of all vulvar malignancies is conducted for those treated at Obstetrics and Gynecology Department of Elche University General Hospital, Alicante, Spain, from 2000 to 2013.
Results: our series included 38 patients. The most frequent neoplasm was squamous cell carcinoma (78.9 %). Global survival at 2 years was 65%. Age, lymph node metastasis, involvement of resection margins and tumor stage, were statistically significant predictors for overall survival.
Conclusions: inguino-femoral lymph node status is an important prognostic factors for overall survival. Conservative surgery improves postoperative morbidity without modifying outcomes.


REFERENCES

  1. Ghurani GB,Peñalver MA.An update on vulvar cáncer.Am J Obstet Gynecol. 2001;185:294-9.

  2. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. Cancer statistics, 2007.CA Cancer J Clin.2007;57:43-66.

  3. Díez J, Moreno J, Pijoán J, Ibáñez E, Aguirreoikoa J, Esteban J, et al. Neoplasias vulvares intraepiteliales e invasivas. Análisis de 142 casos. ProgObstet Ginecol. 2004;47(10):472-9.

  4. Tyring SK. Vulvar squamous cell carcinoma: guidelines for early diagnosis and treatment. Am J Obstet Gynecol. 2003;189:S17-S23.

  5. Salvado C, Alejos A, Iñara M, Esteban E, Manzanera G. Tratamiento quirúrgico del cáncer de vulva. Vulvectomía radical frente a vulvectomía radical modificada. Prog Obstet Ginecol. 2002;45(6):238-44.

  6. Johann S, Klaeser B, Krause T, Mueller MD. Comparison of outcome andrecurrence-free survival after sentinel lymph node biopsy and lymphadenectomy in vulvar cancer. Gynecol Oncol. 2008;110:324-8.

  7. Woelber L, Mahner S, Voelker K, Eulenburg C, Gieseking F, Choschzick M, et al. Clinicopathological prognostic factors and patterns of recurrence in vulvar cancer. Anticancer research. 2009;29:545-52.




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Revista Cubana de Obstetricia y Ginecología. 2016;42