Martínez-Mier G, Ávila-Pardo SF, Irigoyen-Castillo A, Rodríguez-Fernández A, Jiménez-López LA, Varela-Pérez V

Language: Spanish
References: 14
Page: 113-119
PDF size: 250.84 Kb.

ABSTRACT

Introduction: Kidney transplant is the best therapy for most of the patients with end-stage chronic kidney failure. Our program started on September 21 of 2006. Objective: To describe the experience of the kidney transplantation program of our hospital, emphasizing in the patient/graft survival rate and factors that influence graft survival. Material and methods: Retrospective study of kidney transplants performed in our hospital from September 21 of 2006 to the present. Sociodemographic variables, transplant-related variables, serologic status of citomegalovirus, complications, induction, initial and actual immunosuppression were registered. We evaluated acute rejection, kidney function, number and type of infections, causes of death and graft lost. Patient survival and graft non-censored survival to the first, third and fifth year after the transplant was calculated with Kaplan-Meier (log-rank). Results: We performed 95 kidney transplants, 43 living donors and 52 deceased donors. Patient survival at 1, 5 and 10 years was 94.7%, 85.2% and 77.9% respectively. Uncensored graft survival at 1, 5 and 10 years was 87.2%, 59.7% and 43.8% respectively. Delayed graft function, initial immunosuppression, and infections significantly decreased graft survival. Postransplant hospitalizations influenced deceased donor graft survival. Conclusion: Directed attention to anti-infective prophylaxis and immunosuppression regimen in order to improve kidney graft survival in our program.

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