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2016, Number 3

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Rev Mex Traspl 2016; 5 (3)

Transplantation from non-heart-beating donors

Lammel-Lindemann JA, García-Alonso MJ, Flores-Villalba E

Language: Spanish
References: 34
Page: 120-124
PDF size: 224.28 Kb.


ABSTRACT

The use of organs procured from non-heart beating donors can substantially increase the organ pool for transplants. Other countries have had promising results. The general guidelines for these patients, as well as the fact that the Lazarus phenomenon and the dead donor rule exist with their respective wait times and consequences, are different, including ethical and legal aspects. All of the above must be respected and strictly followed with objective decision making and without any bias. It’s extremely important to respect ischemic time limits set for every organ, the time from the life support withdrawal and to try and minimize ischemia time as well as using perfusion machines and drugs that can minimize damage to the organ to be transplanted.


REFERENCES

  1. Blackstock MJ, Ray DC. Organ donation after circulatory death: an update. Eur J Emerg Med. 2014; 21 (5): 324-329.

  2. Barry JM, Murray JE. The first human renal transplants. J Urol. 2006; 176 (3): 888-890.

  3. Starzl TE, Groth CG, Brettschneider L, Penn I, Fulginiti VA, Moon JB et al. Orthotopic homotransplantation of the human liver. Ann Surg. 1968; 168 (3): 392-415.

  4. Calne RY, Rolles K, White DJ, Thiru S, Evans DB, McMaster P et al. Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers. Lancet. 1979; 2 (8151):1033-1036.

  5. Starzl TE, Klintmalm GB, Porter KA, Iwatsuki S, Schröter GPJ. Liver transplantation with use of cyclosporin a and prednisone. N Engl J Med. 1981; 305 (5): 266-269.

  6. Abt PL, Fisher CA, Singhal AK. Donation after cardiac death in the US: history and use. J Am Coll Surg. 2006; 203 (2): 208-225.

  7. A definition of irreversible coma: report of the ad hoc committee of the Harvard Medical School to examine the definition of brain death. JAMA. 1968; 205 (6): 337-340.

  8. Diagnosis of brain death. Statement issued by the Honorary Secretary of the Conference of Medical Royal Colleges and their Faculties in the United Kingdom on 11th October 1976 Ann R Coll Surg Engl. 1977; 59 (2): 170-172.

  9. Dib-Kuri A, Aburto-Morales S, Espinosa-Álvarez A, Sánchez-Ramírez O. Trasplante de órganos y tejidos en México. Rev Investig Clínica. 2005; 57 (2): 163-169.

  10. Orozco-Zepeda H. Un poco de historia sobre el trasplante hepático. Rev Investig Clínica. 2005; 57 (2): 124-128.

  11. Kootstra G, Daemen JH, Oomen AP. Categories of non-heart-beating donors. Transplant Proc. 1995; 27 (5): 2893-2894.

  12. Truog RD, Miller FG, Halpern SD. The dead-donor rule and the future of organ donation. N Engl J Med. 2013; 369 (14): 1287-1289.

  13. Adhiyaman V, Adhiyaman S, Sundaram R. The Lazarus phenomenon. J R Soc Med. 2007; 100 (12): 552-557.

  14. Joffe AR, Carcillo J, Anton N, deCaen A, Han YY, Bell MJ et al. Donation after cardiocirculatory death: a call for a moratorium pending full public disclosure and fully informed consent. Philos Ethics Humanit Med. 2011; 6: 17.

  15. Halazun KJ, Al-Mukhtar A, Aldouri A, Willis S, Ahmad N. Warm ischemia in transplantation: search for a consensus definition. Transplant Proc. 2007; 39 (5): 1329-1331.

  16. Cota N, Burgess M, English W. Organ donation after circulatory death anaesthesia tutorial of the week. 2013; 282.

  17. Moers C, Pirenne J, Paul A, Ploeg RJ. Machine perfusion or cold storage in deceased-donor kidney transplantation. N Engl J Med. 2012; 366 (8): 770-771.

  18. Weeder PD, van Rijn R, Porte RJ. Machine perfusion in liver transplantation as a tool to prevent non-anastomotic biliary strictures: rationale, current evidence and future directions. J Hepatol. 2015; 63 (1): 265-275.

  19. Fondevila C, Hessheimer AJ, Maathuis M-HJ, Muñoz J, Taurá P, Calatayud D et al. Hypothermic oxygenated machine perfusion in porcine donation after circulatory determination of death liver transplant. Transplantation. 2012; 94 (1): 22-29.

  20. Guarrera JV, Henry SD, Samstein B, Odeh-Ramadan R, Kinkhabwala M, Goldstein MJ et al. Hypothermic machine preservation in human liver transplantation: the first clinical series. Am J Transplant. 2010; 10 (2): 372-381.

  21. Guarrera JV, Henry SD, Samstein B, Reznik E, Musat C, Lukose TI et al. Hypothermic machine preservation facilitates successful transplantation of “orphan” extended criteria donor livers. Am J Transplant. 2015; 15 (1): 161-169.

  22. Snoeijs MGJ, Winkens B, Heemskerk MBA, Hoitsma AJ, Christiaans MHL, Buurman WA et al. Kidney transplantation from donors after cardiac death: a 25-year experience. Transplantation. 2010; 90 (10): 1106-1112.

  23. Gagandeep S, Matsuoka L, Mateo R, Cho YW, Genyk Y, Sher L et al. Expanding the donor kidney pool: utility of renal allografts procured in a setting of uncontrolled cardiac death. Am J Transplant. 2006; 6 (7): 1682-1688.

  24. Snoeijs MG, Schaubel DE, Hené R, Hoitsma AJ, Idu MM, Ijzermans JN et al. Kidneys from donors after cardiac death provide survival benefit. J Am Soc Nephrol. 2010; 21 (6): 1015-1021.

  25. Domagala P, Kwiatkowski A, Perkowska-Ptasinska A, Wszola M, Panufnik L, Paczek L et al. Assessment of kidneys procured from expanded criteria donors before transplantation. Transplant Proc. 2009; 41 (8): 2966-2969.

  26. Rudich SM, Kaplan B, Magee JC, Arenas JD, Punch JD, Kayler LK et al. Renal transplantations performed using non-heart-beating organ donors: going back to the future? Transplantation. 2002; 74 (12): 1715-1720.

  27. Weber M, Dindo D, Demartines N, Ambühl PM, Clavien P-A. Kidney transplantation from donors without a heartbeat. N Engl J Med. 2002; 347 (4): 248-255.

  28. Jay CL, Lyuksemburg V, Ladner DP, Wang E, Caicedo JC, Holl JL et al. Ischemic cholangiopathy after controlled donation after cardiac death liver transplantation: a meta-analysis. Ann Surg. 2011; 253 (2): 259-264.

  29. Abt PL, Desai NM, Crawford MD, Forman LM, Markmann JW, Olthoff KM et al. Survival following liver transplantation from non-heart-beating donors. Ann Surg. 2004; 239 (1): 87-92.

  30. De Oliveira NC, Osaki S, Maloney JD, Meyer KC, Kohmoto T, D’Alessandro AM et al. Lung transplantation with donation after cardiac death donors: long-term follow-up in a single center. J Thorac Cardiovasc Surg. 2010; 139 (5): 1306-1315.

  31. Levvey B, Harkess M, Chambers D, Granger E, Ahmed I, Hopkins P et al. 351: Are DCD Lungs Superior? Excellent intermediate results from a donation after cardiac death lung transplant national collaborative. J Heart Lung Transplant. 2010; 29 (2): S117-118.

  32. De Vleeschauwer SI, Wauters S, Dupont LJ, Verleden SE, Willems-Widyastuti A, Vanaudenaerde BM et al. Medium-term outcome after lung transplantation is comparable between brain-dead and cardiac-dead donors. J Heart Lung Transplant. 2011; 30 (9): 975-981.

  33. Wauters S, Verleden GM, Belmans A, Coosemans W, De Leyn P, Nafteux P et al. Donor cause of brain death and related time intervals: does it affect outcome after lung transplantation? Eur J Cardio-Thorac Surg. 2011; 39 (4): e68-76.

  34. Wigfield CH, Love RB. Donation after cardiac death lung transplantation outcomes. Curr Opin Organ Transplant. 2011; 16 (5): 462-468




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