Aguado BOM, Mantilla BDL, Ramos AVD, Pérez MG

Language: Spanish
References: 16
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ABSTRACT

Introduction: scoliosis surgical correction is associated with postoperative severe pain. Postoperative intense pain requires the use of various analgesics and the frequent administration of morphine.
Objective: to evaluate the efficacy of ketamine associated with intraoperative magnesium, in the surgical correction of scoliosis and to correlate it with postoperative pain and the reduction in morphine consumption.
Methods: the natural history of the disease is presented of three patients intervened by scoliosis correction at "Hermanos Ameijeiras" Hospital of Havana (Cuba), and who received, after anesthesia induction, a intravenous bolus of ketamine 0.2 mg/kg and magnesium 50 mg/Kg, followed by a continuous infusion of ketamine 0.15 mg/kg/h y magnesium 8mg/kg/h until extubation. Besides, they received intraoperative multimodal analgesia with nonsteroid antiinflamatories and weak opiates. Pain intensity and the requirements of postoperative salvage analgesia were evaluated; together with the incidence of complications during the 48 hours following the surgical procedure.
Results: all the patients were female. Average age was 18 years. Adequate pain control was achieved, as evaluated mild at every hour when it was measured. Salvage analgesia was not required, neither perioperative complication presented.
Conclusions: the association of ketamine hydrochloride and magnesium sulfate shows good results and open a broad course of study for pain prevention and treatment, with a reduction of polypharmacy and the benefit of the patients’ recovery.

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