medigraphic.com
SPANISH

Revista Cubana de Anestesiología y Reanimación

ISSN 1726-6718 (Electronic)
Revista Cubana de Anestesiología y Reanimación
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2016, Number 2

<< Back Next >>

Revista Cubana de Anestesiología y Reanimación 2016; 15 (2)

Perioperative use of epsilon-aminocaproic acid in patients with the diagnosis of prostatic benign hyperplasia

Fuentes DZ, Rodríguez SOB, López LS
Full text How to cite this article

Language: Spanish
References: 18
Page: 136-144
PDF size: 107.19 Kb.


Key words:

blood transfusion, epsilon-aminocaproic acid, benign prostatic hyperplasia.

ABSTRACT

Introduction: To reduce intraoperative blood loss and the use of transfusion requirements, antifibrinolytic agents that repermeabilize a bleeding vessel are used.
Objective: To determine the behavior of blood loss in patients proposed for surgical treatment due to benign prostatic hyperplasia.
Method: A quasiexperimental study was carried out with a single group in the anesthesiology and resuscitation service of "Manuel Ascunce Domenech" University Hospital in the period from May 1, 2005 to May 1, 2013. For information processing, arithmetic mean was used in the quantitative variables. The qualitative variables are described through absolute and relative frequencies. To calculate the differences between groups, in the case of qualitative variables we used the Chi square test. The significance level used was 0.05. For those variables that differ in the groups to be compared, a multivariate analysis was performed in order to determine whether they have an influence on bleeding or not. The information was processed using SPSS 15.0.
Results: The use of anesthetics and therapeutic methods was associated with Epsilonaminocaproic acid; the risk of blood loss over 750 ml when the anesthetic time and drug are not used was associated with blood loss.
Conclusion: It was shown that the use of Epsilon-aminocaproic acid is a restrictive transfusional measure and an option in patients performed intravesical prostatectomy.


REFERENCES

  1. McCartney S, Guinn N, Roberson R, Broomer B, White W, Hill S, et al and cardiac surgery: a single institution's experience. Transfusion. [Internet] [Citado el 9 de mayo de 2014]. Disponible en http://www.ncbi.nlm.nih.gov/pubmed/24809815

  2. Al-Horani RA, Desai UR. Recent Advances on Plasmin Inhibitors for the Treatment of Fibrinolysis-Related Disorders.Med Res Rev. [Internet] [Citado el 21 de marzo de 2014] Disponible en http://www.ncbi.nlm.nih.gov/pubmed/24659483

  3. Valle EJ, Allen CJ, Van Haren RM, Jouria JM, Li H, Livingstone AS, et al. All trauma patients benefit from tranexamic acid?.J Trauma Acute Care Surg. [Internet] [Citado en junio de 2014] Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/24854303

  4. Verma K, Errico T, Diefenbach C, Hoelscher C, Peters A, Dryer J,et al. Relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: a prospective randomized trial. J Bone Joint Surg Am. 96(10):e80 [Internet] [Citado el 21 de mayo de 2014] Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/24875032

  5. Hui FK, Schuette AJ, Lieber M, Spiotta AM, Moskowitz SI, Barrow DL, et al.e- Aminocaproic acid in angiographically negative subarachnoid hemorrhage patients is safe: a retrospective review of 83 consecutive patients. Neurosurgery. 2012 Mar;70(3):702-5; discussion 705-6. doi: 10.1227/NEU.0b013e3182358cca. [Citado el 8 de abril de 2014] Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/21904257

  6. Cuellar JM, Yoo A, Tovar N, Coelho PG, Jimbo R, Vandeweghe S, et al. The Effects of Amicar and TXA on Lumbar Spine Fusion in an Animal Model.Spine (Phila Pa 1976). [Citado el 26 de junio de 2014]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/24979407

  7. Yeung MC, Tong SY, Tong PY, Cheung BH, Ng JY, Leung GK. Use of viscoelastic haemostatic assay in emergency and elective surgery.Hong Kong Med J. [Citado el 1 de agosto de 2014]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/25082123

  8. Palmer L, Martin L.Traumatic coagulopathy--part 2: Resuscitative strategies. J Vet Emerg Crit Care (San Antonio). 53(1):75-92. [Citado el 24 de enero de 2014] Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/24393363

  9. Milamed.DR, Hedley-Whyte J. Contributions of the surgical sciences to a reduction of the mortality rate in the United States for the period 1968 to 1988. Ann Surg. 1994 Jan; 219(1):94-102. Review. [Citado el 21 de mayo de 2014] Disponible en: http://preview.ncbi.nlm.nih.gov/pubmed/7507658

  10. Matsumoto S, Sekine K, Funaoka H, Yamazaki M, Shimizu M, Hayashida K, et al. Diagnostic performance of plasma biomarkers in patients with acute intestinal ischaemia.Br J Surg. 2014 Feb;101(3):232-8. [Citado el 8 de enero de 2014] Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/24402763

  11. Raveendran R, Wong J.Tranexamic acid: more evidence for its use in joint replacement surgery. Transfusion. [Citado en enero de 2014];54(1):2-15. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/24405302

  12. Afsharimani B, Cabot PJ, Parat MO. Effect of lysine antifibrinolytics and cyclooxygenase inhibitors on the proteolytic profile of breast cancer cells interacting with macrophages or endothelial cells. Br J Anaesth. 2014 Jul;113 Suppl 1:i22-i31. [Citado en julio de 2014] Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/24418973

  13. Gilsanz Rodríguez F. Técnicas de ahorro de sangre: algunas consideraciones. En: Pérez Ferrer A, Gilsanz Rodríguez, Abad Gurumeta A, Narciso del Blanco B,Calvo Vecino LM, et al. Medicina Transfusional. México: Médica Panamericana; 2010.p.1-4

  14. Yang H, Lee J, Seed CR, Keller AJ. Can blood tranfusion transmit cancer a literature review. Transfus Med Rev. 2010; 24(3):235-43. [Citado el 8 de febrero de 2014] Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/20656190

  15. Lundin ES, Johansson T, Zachrisson H, Leandersson U, Bäckman F, Falknäs L,et al. Single-dose tranexamic acid in advanced ovarian cancer surgery reduces blood loss and transfusions: double-blind placebo-controlled randomized multicenter study. Acta Obstet Gynecol Scand. 2014 Apr;93(4):335-44. [Citado el 15 de junio de 2014] Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/24428857

  16. Lippi G, Montagnana M, Franchini M. Ex-vivo red blood cells generation: A step ahead in transfusion medicine. Eur J Intern Med 2011; 22(1):16-9. [Citado el 23 de junio de 2014] Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/21238887

  17. Antoniv TV, Efimochkina KV, Antoniv VF. [Peculiar features of the coagulation, fibrinolytic, and anticoagulation systems of blood in the patients presenting with vascular ENT tumours]. Vestn Otorinolaringol. 2014;(1):17-9. Russian. [Citado el 21 de mayo de 2014] Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/ 24577025

  18. López Gutiérrez J.C. Técnicas quirúrgicas para el ahorro intraoperatorio de sangre. En: Pérez Ferrer A, Gilsanz Rodríguez, Abad Gurumeta A, Narciso del Blanco B, Calvo Vecino LM, et al. Medicina Transfusional. México: Médica Panamericana; 2010.p.137-41.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Revista Cubana de Anestesiología y Reanimación. 2016;15