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2016, Number 6

Gac Med Mex 2016; 152 (6)

Combined heart-kidney transplantation in Mexic

Careaga-Reyna G, Zetina-Tun HJ, Lezama-Urtecho CA; Hernández-Domínguez JM, Santos-Caballero M
Full text How to cite this article

Language: Spanish
References: 14
Page: 783-788
PDF size: 100.64 Kb.


Key words:

Heart-kidney transplantation, Immunosuppression, Terminal cardiac failure, Terminal renal failure.

ABSTRACT

Background: In our country, heart and kidney transplantation is a novel option for treatment of combined terminal heart and kidney failure. This program began in 2012 for selected patients with documented terminal heart failure and structural kidney damage with renal failure. Description of cases: Between January 1, 2012 and April 30, 2016, we made 92 orthotopic heart transplantations. In five of these cases the heart transplantation was combined with kidney transplantation. Results: There were three male and two female patients with a mean age 25.6 ± 5.2 years (range, 17-29). The patients improved their renal function and the heart transplantation was successful with an improved quality of life. One patient died from abdominal sepsis. The other patients are doing well. Conclusion: The combined heart-kidney transplantation is a safe and efficient procedure for patients with structural kidney and heart damage as a cause of terminal failure.


REFERENCES

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  2. Norman JC, Brook MI, Cooley DA, et al. Total support of the circulation of a patient with post-cardiotomy stone-heart syndrome by a partial artificial heart (ALVAD) for five days followed by heart and kidney transplantation. Lancet. 1978;1:1125-7.

  3. Leeser DB, Jeevanandamb V, Furukawaa S, et al. Foster CE IIId.Simultaneous heart and kidney transplantation in patients with end-stage heart and renal failure. Am J Transplant. 2001;1:89-92.

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  9. Narula J, Bennett LE, DiSalvo T, Hosenpud JD, Semigran Mj, Dec GW. Outcomes in recipients of combined heart-kidney transplantation: multiorgan, same-donor study of the International Society of Heart and Lung Transplantation/United Network for Organ Sharing Scientific Registry. Transplantation. 1997;63(6):861-7.

  10. Bruschi G, Busnach G, Colombo T, et al. Long-term follow-up of simultaneous heart and kidney transplantation with single donor allografts: report of nine cases. Ann Thorac Surg. 2007;84(2):522-7.

  11. Pinderski LJ, Kirklin JK, McGiffin D, et al. Multi-organ transplantation: is there a protective effect against acute and chronic rejection? J Heart Lung Transplant. 2005;24(11):1828-33.

  12. Gill J, Shah T, Hristea J, et al. Outcomes of simultaneous heart-kidney transplant in the US: a retrospective analysis using OPTN/UNOS data. Am J Transplant. 2009;9(4):844-52.

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Gac Med Mex. 2016;152