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ISSN 1727-897X (Electronic)

2016, Number 6

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Medisur 2016; 14 (6)

Meningoencephalitis by Cryptococcus. Case presentation

Reyes RI, Urdanivia CMO, Pórtela SM

Language: Spanish
References: 12
Page: 784-788
PDF size: 146.16 Kb.


ABSTRACT

Cryptococcus neoformans is a yeast-capped fungus, with marked neurotropism; it is the causal agent of cryptococcosis, deep fungal infection, of sub-acute or chronic course, considered as opportunistic. Cryptococcal meningitis presents distinctive clinical characteristics. In most cases it is acquired out of the hospital and develops sub acutely. If it is not treated it can be fatal in a few weeks. For these reasons it was decided the publication of this case of a 60 year old female patient who was brought to the "Gustavo Aldereguía" Hospital in Cienfuegos, with headache and loss of consciousness. On questioning there was information of a personal antecedent of headaches without apparent cause for some time ago. She was admitted conscious at the ICU. Some tests were performed, among them, microbiological study of cerebrospinal fluid and blood culture samples were taken , according to the standards established , were Cryptococcus neoformans was isolated. Unfortunately after having been diagnosed the patient died.


REFERENCES

  1. Brandt M, Severo L. Criptococosis. En: Heymann DL, editores. El control de las enfermedades transmisibles. Washington: OPS; 2011. p. 108-9

  2. Da Silva BK, Freire AK, Bentes Ados S, Sampaio IL, Santos LO, Dos Santos MS, et al. Characterization of clinical isolates of the Cryptococcus neoformans-Cryptococcus gattii species complex from the Amazonas State in Brazil. Rev Iberoam Micol [revista en Internet]. 2012 [citado 20 Ene 2014];29(1):[aprox. 4p]. Disponible en: http://www.reviberoammicol.com/2012-29/040043.pdf

  3. Tello M, Gutiérrez E, Béjar V, Galarza C, Ramos W, Ortega AG. Criptococosis. Rev Méd Risaralda. 2013;19(2):147-53

  4. Paz Rodríguez MT. Neurocriptococosis crónica en un paciente inmunocompetente. Rev Ciencias Médicas [revista en Internet]. 2014 [citado 20 Ene 2014];18(6):[aprox. 8p]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-31942014000600020

  5. Rocha KC, Pinhal C, Cavalcanti S, Vidal M, Toscano M, Moraes Vasconcelos D, et al. Lymphocyte transformation assay for C neoformans antigen is not reliable for detecting cellular impairment in patients with Neurocryptococcosis. BMC Infect Dis [revista en Internet]. 2012 [citado 15 Ene 2014];12:[aprox. 11p]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556098/

  6. Illnait Zaragozí MT, Martínez Machín GF, Fernández Andreu CM, Hagen F, Boekhout T, Klaassen CH, et al. Microsatellite typing and susceptibilities of serial Cryptococcus neoformans isolates from Cuban patients with recurrent cryptococcal meningitis. BMC Infect Dis [revista en Internet]. 2010 [citado 12 Feb 2014];10:[aprox. 12p]. Disponible en: http://www.biomedcentral.com/1471-2334/10/289/

  7. Illnait Zaragozí MT, Martínez GF, Fernández Andreu CM, Marchena Bequer JJ, Perurena MR. Contribución al estudio de la criptococosis infantil en Cuba. Rev Cubana Med Trop [revista en Internet]. 2013 [citado 12 Feb 2014];65(1):[aprox. 13p]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0375-07602013000100009

  8. Casadevall A. Cryptococci at the brain gate: break and enter or use a Trojan horse?. J Clin Invest. 2010;120:1389-92

  9. Calderón F, Ibáñez C, González-Hernández J. Meningitis criptocócica en paciente VIH positivo: Revisión a propósito de un caso clínico. Revista Memoriza.com. 2009;5:34-44

  10. Gámez Rodríguez O, Romero Calzado D, Bizet Altes O. Meningoencefalitis letal por criptococosis en una mujer de mediana edad. MEDISAN [revista en Internet]. 2013 [citado 12 Feb 2014];17(10):[aprox. 7p]. Disponible en: http://bvs.sld.cu/revistas/san/vol17_10_13/san151710.htm

  11. Martínez Machín G, Barrial de la Rosa L, Illnait Zaragozí M, Valdés Hernández IC, Fernández Andreu CM, Perurena MR, et al. Utilidad de la D-prolina en la diferenciación de las variedades de Cryptococcus neoformans. Rev Cubana Med Trop. 2004;56(1):77-9

  12. Fernández Andreu CM, Martínez Machín G, Illnait MT, Perurena Lancha MR, González Miranda M. Identificación de Cryptococcus neoformans var. neoformans en aislamientos clínicos cubanos. Rev Cubana Med Trop. 1998;50(2):12-8




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