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Órgano Oficial de la Asociación Mexicana de Hepatología

2017, Number 1

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Ann Hepatol 2017; 16 (1)

Ironing out Steatohepatitis

Subramaniam VN

Language: English
References: 8
Page: 8-9
PDF size: 116.29 Kb.


Text Extraction

The increasing prevalence of obesity and the metabolic syndrome worldwide is well recognized, the tight association of non-alcoholic fatty liver disease (NAFLD) with these conditions increasingly so. NAFLD can progress to the more severe form of the disorder non-alcoholic steatohepatitis (NASH), which is characterized by worsening liver pathology. The prevalence of iron disorders, in particularly the genetic iron overload disorder hereditary hemochromatosis, is also high in the European population; up to 1:200 individuals carry the at-risk gene variant –the p.C282Y mutation in the HFE gene– which results in significant hepatic iron accumulation.


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