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2016, Number 3

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Revista Cubana de Obstetricia y Ginecología 2016; 42 (3)

Sepsis in patients with preterm premature rupture of membranes

Sarduy RMC, Sánchez RN, Rodríguez MA

Language: Spanish
References: 32
Page: 330-343
PDF size: 124.39 Kb.


ABSTRACT

Introduction: prematurity is one of the great challenges faced by perinatal medicine at present.
Objective: characterize perinatal sepsis in pregnant women with premature rupture of membranes and preterm delivery between weeks 28 and 36.6 at "Ramón González Coro" Obstetrics and Gynecology Hospital.
Methods: a cross-sectional observational retrospective study was conducted of 33 medical records from January to December 2008. A form was developed to collect data such as maternal age, risk factors, gestational age at admission, type of delivery and types of sepsis according to laboratory tests.
Results: of the total pregnant women, 42,5 % were in the 20-29 age group, 36,4 % were admitted at 34-36 weeks of pregnancy, 51,4 % had anemia, and 69,7 % underwent cesarean section, 58,3 % had sepsis, and 41,7 % had positive leukocyte counts.
Conclusions: the predominant maternal age was 20-29 years, whereas gestational age at admission was 34-36 weeks. Anemia was the most common risk factor. There was a predominance of cesarean delivery with increased sepsis, and there was a higher proportion of positive leukocyte counts in neonatal sepsis.


REFERENCES

  1. Romero R. The preterm Labour syndrome. En: Elder MG, Lamont F, Romero R. editor, Preterm Labour: New York: Churchill Livingstone; 1997. Vol 2. p.29-49.

  2. Cabero L, Ingermarsson I. Parto prematuro. Aspectos de géneros del nacimiento pretérmino. Ed. Med Panamericana S.A. 2004;30(5):47-51.

  3. Cunninghan F. Williams Obstetric. 21 Ed. 2002. XVI CURSO Vol II. p. 604-623.

  4. Cabero Roura JM. Lailla Vicens. XVI Curso intensivo de formación continuada. Centro Español de Derechos Reprográficos. [citado 13 de noviembre 2013]. Disponible en: www.cedro.org.2008

  5. Ovalle A, Martínez MA, Ferrand P, Peña V, Ocaranza M, Schwarze JE. Infección intraamniótica por Neisseria Gonorrhoeae en un caso de rotura prematura de membranas de pretérmino. Rev Chil Obstet Gynecol. 1999;64(2):130

  6. Keelan JA, Yang J, Romero R, Chaiworapongsa T, Marvin KM, Sato TA, et al. Epithelial cell-derived neutrophil-activating peptide-78 is present in fetal membranes and amniotic fluid at increased concentrations with intra-amniotic infection and preterm delivery. Biol of Reproduc. 2004;70:253-9.

  7. Gary A. Dildy III, MD, Menachem (Obstet Gynecol 2007;109:863-9) Mc.Donald H. et al. Antibiotic for Treating Bacterial Vaginitis in pregnancy:Cochran Data Base Syst Rev. 2007 (1):CD 000262.

  8. Suardíaz J, Cruz C, Colina A. Laboratorio Clínico. Editorial Ciencias Médicas: La Habana; 2004.

  9. Piloto Morejón M, Suárez Blanco C, Palacios Valdés G. Complicaciones puerperales durante la estadía hospitalaria. Rev Cubana Obstet Ginecol. 2002[citado enero de 2013];28(1):1-3. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-600X2002000100007

  10. Edwards RK, Locksmith J, Duff P. Expanded spectrum antibiotics with preterm premature rupture of the membranes. Obstet Gynecol. 2000;96:60-4.

  11. Romero Arauz JF, Martínez Chéquer JC, Garcia Alonso LA, Jurado Hernández VH, Ayala Méndez JA. Utilidad del perfil biofísico fetal en la rotura prematura de membranas pretérmino con tratamiento. Ginecol Obstet Mex. 2005;73:415-23.

  12. Cruz GM. Test para la profilaxis de la prematuridad. [Tesis doctorado]. Facultad de Ciencias Médicas "Mariana Grajales Coello". Universidad de Santiago de Cuba. 2008.

  13. Andersson B, Hagberg H, Holst RM, Jacobsson BO, Lilja H, Wennerholm UB. Monocyte chemotactic protein-1 in cervical and amniotic fluid: Relationship to microbial invasion of the amniotic cavity, intra-amniotic inflammation, and preterm delivery. Am J Obstet Gynecol. 2003;189:1161-67.

  14. Lee MJ, Davies J, Guinn D, Sullivan L, Atkinson W, McGregor S, et al. Dosis única versus repetida de corticoides antenatales en rotura Prematura de Membranas de Pretérmino. Obstet Gynecol. 2004;103(2):274-81.

  15. Ghidini A, Salafia CM, Kirn V, Doria V. Biophysical profile in predicting acute ascending infection in preterm rupture of the membranes before 32 weeks. Obstet Gynecol. 2000;96:201-6.

  16. Edwards RK, Locksmith J, Duff P. Expanded spectrum antibiotics with preterm premature rupture of the membranes. Obstet Gynecol. 2000;96:60-4.

  17. González González NL, Medina V, Jimenez A, Gomez Arias J, Ruano A, Perales A, et al. Base de Datos Perinatales Nacionales 2004. Prog Obstet Ginecol. 2006;49:645-55.

  18. Grant A. Glazener. Cesarean section versus expectant management for delivery of the small baby. Chest. 2003;4(27):12-20.

  19. Blumenfeld YJ, Lee HC, Gould JB, Langen ES, Jafari A, El-Sayed YY. The Effect of Preterm Premature Rupture of Membranes on Neonatal Mortality. 2010;16(6):100-116.

  20. Janek B, Rangit A, Walter V, Argyro S, Nicolaides K. Prediction of spontaneous preterm delivery from maternal factors, obstetrics history and placental perfusion and function at 11-13 weeks. Prenat Diagnosis. 2011;31:75-83.

  21. Scott NC, Gregory K, Hobel C. Premature rupture of the membranes: an evidence based approach to clinical care. Am J Perinatol. 2001;18:397-412.

  22. Armson A, O'Conell C, Person V. Determinants of perinatal mortality and serious neonatal morbidity. Obstet Gynecol. 2006;108:556-64.

  23. Ovalle A, Martínez MA, Poblete IP, Fuentes A, Villablanca E, Gómez R, et al. Microbiología aislada en la rotura prematura de membranas de pretérmino. Relación con morbilidad infecciosa materna, neonatal e intervalo rotura de membranas parto. Rev Chil Obstet Ginecol. 1995;60(4):252-62.

  24. Ovalle A, Martínez MA, Ferrand P, Peña V, Ocaranza M, Schwarze JE. Infección intraamniótica por Neisseria Gonorrhoeae en un caso de rotura prematura de membranas de pretérmino. Rev Chil Obstet Gynecol. 1999;64(2):130-2.

  25. National office of statistics. Preterm Birth in England and Wales. [citado octubre 2007] Disponible en: http://ww.statistics.gov.uk(pdfdir/preterm 0507.pdf

  26. Woods JR. Pathobiology: Oxidant stress, angiogenesis and neoplasia. Reactive Oxygen Species and Preterm Premature Rupture of Membranes. A Review Placenta. Trophoblast Research. 2001;15(Suppl 22ª):538-44.

  27. Flenady V, King J. Antibióticos para la rotura prematura de membranas antes del parto a término o cerca del término (Revisión Cochrane traducida). En: La Biblioteca Cochrane Plus. 2007(4). Oxford, Update Software Ltd. [citado 10 de septiembre 2013]Disponible en: http://www.update-software.com (Traducida de The Cochrane Library. Chichester, UK: John Wiley & Sons, Ltd. 2007(4)).

  28. Jacobson B, Ladfors L, Milsomt I. Advanced maternal age and adverse perinatal outcome. Obstet Gynecol. 2004;104:727-33.

  29. Tillett WS, Francis Jr T. Serological reactions in pneumonia with a nonprotein somatic fraction of pneumococcus. (pdf). J Exp Med. 1990[citado 10 de septiembre 2013];10 (52):561-85. Disponible en: http://www.jem.org/cgi/

  30. Lobo SMA, Lobo FRM, Peres Bota D, Lopes-Ferreira F, Soliman HM, Mélot C, et al. C-reactive protein levels correlate with mortality and organ failure in critically ill patients. Doctorat en Santé des Populations. Faculté des sciences de la santé Université d’Ottawa . 2003;23(7):102-28.

  31. Parry S, Strawss JF. Premature rupture of the fetal membranes. N Engl J Med. 1998;338(10):663-71.

  32. Hunter J, Bevilaqua MP. Endotheline leukocyte Adhesion Molecules. Ann revs Immunology.1993; p. 767-804.




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