2017, Number 1
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ABSTRACTAdipose tissue is currently recognized as an organ with an important endocrine function. Two main types of adipose tissue are distinguished: the brown and the white. Adipose tissue can secrete a variety of substances known as adipokines that are implicated in the regulation of body weight, the immune system and the vascular functioning and the insulin sensitivity. In cases of obesity (mainly visceral obesity), proinflammatory adipokines are increased. They are commonly associated with clinical and subclinical inflammation, insulin resistance, oxidative stress and endothelial injury. Proinflammatory adipokines also play a key role in the metabolic syndrome and increase cardiometabolic risk. The present review is aimed at exposing the morphofunctional characteristics of adipose tissue and the mechanisms that link this tissue to the origin of a variety of diseases.
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