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ISSN 0028-3851 (Print)

2004, Number 1

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Rev Neurol Neurocir Psiquiat 2004; 37 (1)

Neurodegeneration and Alzheimer disease

Silva EJG, Islas MJ

Language: Spanish
References: 11
Page: 25-28
PDF size: 141.05 Kb.


ABSTRACT

Alzheimer disease is a progressive dementia which clinical course includes mainly a gradual and progressive loss of intellectual capacity and constitutes one of the degenerative diseases of the nervous system, which are characterized by neuronal death of gradual and progressive evolution through many years. Prevalence data are from 3% in people between 65 to 74 years old and of 18.7% for those between 75 and 84 years old.
In this paper a review is done, describing neurodegenerative and epidemiological aspects, as well as diagnostic and neuropathological criteria. It is emphasizes the findings that pointed out the tau protein as the main component in helicoidal peer filaments that conform neurofibrillary tangles and neuritic dystrophic cortical plaques.
Finally, it is alluded to the current ongoing advances in various parts of the world and its potential impact in the quality of life of people in the third age to favor a successful aging.


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