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ISSN 2007-6800 (Print)

2017, Number 1

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Rev Mex Traspl 2017; 6 (1)

Renal function and proteinuria in donors before and after nephrectomy

García-Velásquez DP, Vanegas-Ponce H, Gómez-de Ossio MD

Language: Spanish
References: 19
Page: 12-17
PDF size: 213.91 Kb.


ABSTRACT

Introduction: Renal donation involves physiological changes in the donors. Studies on the risks and morbimortality in these remain controversial. It has not been determined whether there is a greater tendency to develop complications after the donation. Objective: To compare the renal function and proteinuria in renal donors before and after nephrectomy in a population of the northeast of Mexico. Material and methods: Observational, analytic, longitudinal, retrospective study. We included patients who were nephrectomized for donation between January 2012 and December 2013, followed in urology consultation, and who had their 24-hour creatinine clearance and proteinuria evaluated before and two months after nephrectomy. For the descriptive analysis, absolute frequencies, percentages, medias and medians were measured with standard deviation or limits. For the inferential analysis, T Student distribution or Wilcoxon test were used. A p-value ‹ 0.05 was considered significant. The statistical package SPS 15.0 was used. Results: One hundred five patients were included. There was a significant decrease in creatinine clearance before and after the nephrectomy (p ‹ 0.001). Regarding proteinuria, there was an increase after the surgery (p = 0.012). Conclusion: There is a significant decrease in creatinine clearance, as well as an increase in proteinuria after nephrectomy.


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