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2017, Number 1

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Anales de Radiología México 2017; 16 (1)

Incidence of occult breast cancer with ganglion metastasis, image findings

García-Verastegui LS, Ríos-Rodríguez N, Tenorio-Flores E, García-Blanco MC
Full text How to cite this article

Language: Spanish
References: 9
Page: 3-13
PDF size: 428.15 Kb.


Key words:

mammogram, ultrasound, occult breast cancer, annual incidence, histopathological result.

ABSTRACT

Introduction: occult breast cancer is presently defined as a neoplasm which manifests with a metastatic axillary ganglion, without clinical or image manifestation of the primary tumor in the breast. This form of neoplastic presentation is low, on the order of 0.3 to 1% of all breast cancers.
Objetive: determine the incidence of occult breast cancer in women attended at Hospital General de Mexico in the period 2012-2015.
Material and Method: we conducted a transverse, descriptive and retrospective study, including patients with diagnosis of occult breast cancer, confirmed by histopathological study, who were attended at Hospital General de Mexico in the period between 2012 and 2015. Such patients underwent an image study, in accordance with the lexicon of the 5th edition of BI-RADS. (ultrasound, mammogram, or magnetic resonance) using two Giotto digital mammographs. Breast ultrasounds were taken with an Acuson Antares Premium Edition, with 7 to 13 MHz linear transductors, operated by radiologists specialized in breast imaging. The studies were interpreted on reading monitors as specified in Official Mexican Standard 229- SSA2-2011, using the picture archiving and communication system (PAC-RIS). Ethical aspects: in accordance with the Regulations to the General Law on Healthcare in matters of healthcare research, the investigation was considered risk-free.
Results: the incidence of breast cancer per year was 2.5%, with a total of 7 patients in the period 2013-2015, who were included in the study. 100% were female, with diagnosis of occult breast cancer with metastasis in ipsilateral axillary lymph nodes and pathology report of infiltrating ductal carcinoma, most in an age range of 50 to 59 years, with a mean age of 58.5 years.
Conclusion: the incidence in the years 2013 to 2015 was 2.5%, approximately, in each year, above that reported in the literature (0.03-01%), which indicates that we should place greater emphasis on clinical data reported by the patient, on palpation, and on mammograms with type C fibroglandular pattern as defined by the American College of Radiology.


REFERENCES

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  2. Phillips J. Manno L. Poorly diferenciated carcinoma of unknown primary involving the axila. Medscapescme. 2008;27:329.

  3. Olson JA Jr, Morris EA, Van Zee KJ. Magnetic resonance imaging facilitates breast conservation for occult breast cancer. Ann Surg Oncol 2000;7:411-5.

  4. American College of Radiology. Breast Imaging Reporting and DataSystem (BI-RADS). 4th ed. USA. American College of Radiology. 2013.

  5. Hollingsworth AB, Stough RG, O´Dell CA, Brekke CE. Breast magnetic resonance imaging for preoperative locoregional staging. Am J Surg. 2008;196:38997.

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  7. American Joint Committee on Cancer Staging System for Breast Cancer (AJJCC Cancer Staging Manual, Sixth Edition, 2002).

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  9. Kwen Lee, Ricardo schatrz J. Cáncer oculto de mama: Dos casos clínicos analizados según concepto actual. Rev Med Chile. 2006;134:116670.




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