Rodríguez-Segura A, Montoya-García C, Pacheco-López RC

Language: Spanish
References: 12
Page: 132-139
PDF size: 280.52 Kb.

ABSTRACT

Currently facial skin aging is very important as it is a complex process that involves every cell and organ in the human body, which leads to deterioration of cell functions. The aging phenomenon can be interpreted as a sign of old age at the level of all cells, which is why the application of platelet rich plasma as a potentiating tool to improve clinical and histological characteristics of tissues made up of cells with receptors for platelet growth factor, is a good option to achieve facial rejuvenation. The objective of this study was to evaluate the clinical and histological changes with the application of platelet-rich plasma. An experimental, longitudinal biomedical and clinical study was performed that included 23 patients from 30 to 70 years old, workers of the morning shift of «Dr. Rubén Leñero» General Hospital, two men and 21 women, who showed dissatisfaction with the characteristics of their facial skin, and accepted the application of platelet rich plasma with 2 mm biopsy in the malar region under topical and local anesthesia respectively, and photographic control. Such applications were carried out three times on each patient with an interval of three weeks. Histological tests were performed for collagen and elastin. According to the results of the satisfaction survey 91% were satisfied and 9% very satisfied. Regarding the histological features, changes in the dermis were observed, with a tendency to papillary cells; the thickness of collagen in papillary and as well as reticular dermis, and the thickness and characteristics of the elastic fibers showed a tendency to improve. We concluded that platelet rich plasma optimizes the clinical characteristics improving hydration, color, texture, tone, presence of nasolabial folds, open pores, eyelid bags and acne breakouts and histologically increases cell activity, improves the characteristics of collagen and elastin, therefore it is a safe procedure for facial rejuvenation.

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