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2016, Number 4

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Revista Cubana de Obstetricia y Ginecología 2016; 42 (4)

Characterization of patients with HELLP syndrome

Álvarez SAZ, Álvarez PVA, Martos BFD

Language: Spanish
References: 15
Page: 443-450
PDF size: 130.55 Kb.


ABSTRACT

Introduction: HELLP syndrome is a complication of hypertensive disorders in pregnancy.
Objective: To identify the characteristics of patients who suffer it.
Methods: A retrospective, cross-sectional and descriptive study was carried out in Hospital Osio de Cua, Urdaneta municipality, state of Miranda in the Bolivarian Republic of Venezuela since the creation of the intensive care unit in the period of September 2010 through June 2012. The sample was made up of 35 patients who were admitted to the unit with diagnosis of HELLP syndrome or were so diagnosed during their stay at hospital. The primary data source was the medical history and the intensive care unit records.
Results: The predominant factors were found to be maternal age of 20 to 29 years (57.14%) and gestational age of 28 to 34 weeks (42.87%) at the time of pregnancy cessation. The most frequent causes of admission were epigastralgia and high blood pressure figures. According to the platelet count (48.58%), the most common type was HELLP II; 80% of patients showed hemoglobin values lower than 100g/l and 88.58% had high transaminase levels whereas 82.85% of the renal profile values were over the normal figures. During pregnancy, the disease affected 75% of studied females.
Conclusions: HELLP syndrome is a pathological process that may occur in pregnancy or in puerperium.


REFERENCES

  1. Audibert F, Friedman S, Frangieh A, Sibai B. Clinical utility of diagnostic criteria for the HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome. Am J Obstet Gynecol. 1996;175:460-4.

  2. Hipertensión arterial y embarazo ISBN 978-212-871-2. editado 2013 . publicado en Biblioteca Virtual de Salud. Ecimed.

  3. Foley MR, StrongT, Garite T. Cuidados intensivos en obstetricia. En:SibaiBM. Emergencias Hipertensivas. 3ª ed. Venezuela:Amolca; 2011.p.49-60.

  4. De la Rubia J, Pérez F, Navarro A. Diagnóstico y tratamiento. Síndrome Hellp Medicina Clínica Barcelona [serie en Internet]. 2001[citado 20 de diciembre de 2015];117(2):[aprox.64p]. Disponible en: http://www.doyma.es18/12/2006

  5. Breve historia del Síndrome de HELLP [Internet] 2008 [citado Julio 2012]. Disponible en: http://www.obstetriciacritica.com.ar

  6. Romero JF,Tena G, Jiménez S. Enfermedades hipertensivas del embarazo. En: Romero JF. Historia de la preeclampsia. México:Mc Graw Hill; 2009.p.2-3.

  7. Weinstein L. Syndrome of haemolysis, elevated liver enzymes, and low platelets count: A severe consequence of hypertension in pregnancy. Am J Obstet Gynecol. 1982;142:159-67.

  8. Soto F, Rivera L, Estévez M, Ayala V, Cabrera C. Síndrome HELLP: morbilidadmortalidad materna y perinatal. Rev Obstet Ginecol Venez. 2014;74(4):244-51.

  9. Cabero RL, Saldívar Rodríguez D, Cabrillo Rodríguez E. Obstetricia y Medicina Materno-Fetal. En: Llurva OE, Cabero RL. Síndrome de HELLP. Madrid: Médica Panamericana; 2007. p.575-679.

  10. Barton JR, Sibai BM. Prediction and prevention of recurrent preeclampsia. Obstet Gynecol. 2008;112:359-72.

  11. García Velázquez V, Echavarría Restrepo LG, Ardila Castellanos R, Gutiérrez Marín J. Hallazgos clínicos y de laboratorio que sugieren tempranamente el síndrome de hellp en pacientes con preeclampsia severa. Rev chil obstet ginecol. 2014;79(1):9-13.

  12. Martin JN Jr, May WL, Magann EF, Terrone DA, Rinehart BK, Blake PG. Early risk assessment of severepreeclampsia: admission battery of symptoms and laboratory tests to predict likelihood of subsequent significant maternal morbidity. Am J Obstet Gynecol. 1999;180:1407-14.

  13. Carpani G, Bozzo M, Ferrazzi E, D'Amato B, Pizzotti D, Radaelli T, et al. The evaluation ofmaternal parameters at diagnosis may predict HELLP syndrome severity. J Matern Fetal Neonatal Med. 2003;13:147-51.

  14. Von Dadelszen P, Payne B, Li J, Ansermino JM, Broughton Pipkin F, Cote AM, et al. PIERS Study Group. Prediction of adverse maternal outcomes in pre-eclampsia: development and validation of the full-PIERS model. Lancet. 2011;377(9761):219-27.

  15. Jiménez Fiz Y, Roura Carrasco JO, Caveda Estela OG, Arévalo Tan CE. Síndrome de HELLP en una unidad de cuidados intensivos polivalente AMC. 2014;18(5).




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